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AAV-mediated gene transfer of DNase I in the liver of mice with colorectal cancer reduces liver metastasis and restores local innate and adaptive immune response.
Xia, Yujia; He, Jiayi; Zhang, Hongji; Wang, Han; Tetz, George; Maguire, Casey A; Wang, Yu; Onuma, Amblessed; Genkin, Dmitry; Tetz, Victor; Stepanov, Alexey; Terekhov, Stanislav; Ukrainskaya, Valeria; Huang, Hai; Tsung, Allan.
Afiliação
  • Xia Y; Division of Surgical Oncology, Department of Surgery, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
  • He J; Department of Gastroenterology, Tongji Medical College, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, China.
  • Zhang H; Division of Surgical Oncology, Department of Surgery, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
  • Wang H; Department of Pediatrics, Tongji Medical College, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, China.
  • Tetz G; Division of Surgical Oncology, Department of Surgery, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
  • Maguire CA; Division of Surgical Oncology, Department of Surgery, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
  • Wang Y; Department of Gastroenterology, Tongji Medical College, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, China.
  • Onuma A; Human Microbiology Institute, New York, NY, USA.
  • Genkin D; CLS-Therapeutics, New York, NY, USA.
  • Tetz V; Molecular Neurogenetics Unit, Harvard Medical School, Massachusetts General Hospital, Charlestown, MA, USA.
  • Stepanov A; Division of Surgical Oncology, Department of Surgery, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
  • Terekhov S; Division of Surgical Oncology, Department of Surgery, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
  • Ukrainskaya V; CLS-Therapeutics, New York, NY, USA.
  • Huang H; Human Microbiology Institute, New York, NY, USA.
  • Tsung A; M.M. Shemyakin and Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Mol Oncol ; 14(11): 2920-2935, 2020 11.
Article em En | MEDLINE | ID: mdl-32813937

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Desoxirribonuclease I / Neoplasias Hepáticas Limite: Animals / Female / Humans / Male Idioma: En Revista: Mol Oncol Assunto da revista: BIOLOGIA MOLECULAR / NEOPLASIAS Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Desoxirribonuclease I / Neoplasias Hepáticas Limite: Animals / Female / Humans / Male Idioma: En Revista: Mol Oncol Assunto da revista: BIOLOGIA MOLECULAR / NEOPLASIAS Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos