High intratumoral CD8<sup>+</sup> T-cell infiltration is associated with improved survival in prostate cancer patients undergoing radical prostatectomy.

Yang, Yuanquan; Attwood, Kristopher; Bshara, Wiam; Mohler, James L; Guru, Khurshid; Xu, Bo; Kalinski, Pawel; Chatta, Gurkamal

High intratumoral CD8⁺ T-cell infiltration is associated with improved survival in prostate cancer patients undergoing radical prostatectomy.

Yang, Yuanquan; Attwood, Kristopher; Bshara, Wiam; Mohler, James L; Guru, Khurshid; Xu, Bo; Kalinski, Pawel; Chatta, Gurkamal.

Afiliação

Yang Y; Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA.
Attwood K; Division of Medical Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, USA.
Bshara W; Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA.
Mohler JL; Department of Pathology, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA.
Guru K; Department of Urology, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA.
Xu B; Department of Urology, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA.
Kalinski P; Department of Pathology, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA.
Chatta G; Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA.

Prostate ; 81(1): 20-28, 2021 01.

Article em En | MEDLINE | ID: mdl-33085799

Assuntos

Linfócitos T CD8-Positivos/imunologia; Linfócitos do Interstício Tumoral/imunologia; Neoplasias da Próstata/imunologia; Adulto; Idoso; Linfócitos T CD8-Positivos/patologia; Estudos de Coortes; Humanos; Linfócitos do Interstício Tumoral/patologia; Masculino; Pessoa de Meia-Idade; Análise Multivariada; Estadiamento de Neoplasias; Prognóstico; Prostatectomia; Neoplasias da Próstata/mortalidade; Neoplasias da Próstata/cirurgia; Estudos Retrospectivos; Taxa de Sobrevida

Palavras-chave

immunohistochemistry; prostate cancer; radical prostatectomy; tumor infiltrating lymphocyte; tumor tissue microarray

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Linfócitos do Interstício Tumoral / Linfócitos T CD8-Positivos Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Humans / Male / Middle aged Idioma: En Revista: Prostate Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos

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