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Ribosome-Targeting Antibiotics Impair T Cell Effector Function and Ameliorate Autoimmunity by Blocking Mitochondrial Protein Synthesis.
Almeida, Luís; Dhillon-LaBrooy, Ayesha; Castro, Carla N; Adossa, Nigatu; Carriche, Guilhermina M; Guderian, Melanie; Lippens, Saskia; Dennerlein, Sven; Hesse, Christina; Lambrecht, Bart N; Berod, Luciana; Schauser, Leif; Blazar, Bruce R; Kalesse, Markus; Müller, Rolf; Moita, Luís F; Sparwasser, Tim.
Afiliação
  • Almeida L; Institute of Infection Immunology, TWINCORE, Center for Experimental and Clinical Infection Research, Hannover Medical School and the Helmholtz Center for Infection Research, Hannover 30625, Germany; Institute of Medical Microbiology and Hygiene, University Medical Center of the Johannes Gutenberg-U
  • Dhillon-LaBrooy A; Institute of Infection Immunology, TWINCORE, Center for Experimental and Clinical Infection Research, Hannover Medical School and the Helmholtz Center for Infection Research, Hannover 30625, Germany; Institute of Medical Microbiology and Hygiene, University Medical Center of the Johannes Gutenberg-U
  • Castro CN; Institute of Infection Immunology, TWINCORE, Center for Experimental and Clinical Infection Research, Hannover Medical School and the Helmholtz Center for Infection Research, Hannover 30625, Germany.
  • Adossa N; QIAGEN, Aarhus C 8000, Denmark; University of Turku, Computational Biomedicine, Turku Center for Biotechnology, Turku 20520, Finland.
  • Carriche GM; Institute of Infection Immunology, TWINCORE, Center for Experimental and Clinical Infection Research, Hannover Medical School and the Helmholtz Center for Infection Research, Hannover 30625, Germany; Institute of Medical Microbiology and Hygiene, University Medical Center of the Johannes Gutenberg-U
  • Guderian M; Institute of Infection Immunology, TWINCORE, Center for Experimental and Clinical Infection Research, Hannover Medical School and the Helmholtz Center for Infection Research, Hannover 30625, Germany.
  • Lippens S; VIB Imaging Core Facility Gent, Gent 9052, Belgium.
  • Dennerlein S; Department of Cellular Biochemistry, University Medical Center, Göttingen 37073, Germany.
  • Hesse C; Fraunhofer Institute for Toxicology and Experimental Medicine (ITEM), Hannover 30625, Germany.
  • Lambrecht BN; VIB-UGent, Center for Inflammation Research, Gent 9052, Belgium.
  • Berod L; Institute of Infection Immunology, TWINCORE, Center for Experimental and Clinical Infection Research, Hannover Medical School and the Helmholtz Center for Infection Research, Hannover 30625, Germany; Institute of Molecular Medicine, University Medical Center of the Johannes Gutenberg-University Main
  • Schauser L; QIAGEN, Aarhus C 8000, Denmark.
  • Blazar BR; Department of Pediatrics, Division of Blood and Marrow Transplantation, University of Minnesota, Minneapolis, MN 55454, USA.
  • Kalesse M; Institute for Organic Chemistry, Leibniz University Hannover, Hannover, Germany; Helmholtz Center for Infection Research (HZI), Braunschweig 38124, Germany.
  • Müller R; Helmholtz Institute for Pharmaceutical Research, Helmholtz Center for Infection Research and Department of Pharmaceutical Biotechnology, Saarland University, Saarbrücken 66123, Germany.
  • Moita LF; Innate Immunity and Inflammation Laboratory, Instituto Gulbenkian de Ciência, Oeiras, Portugal.
  • Sparwasser T; Institute of Infection Immunology, TWINCORE, Center for Experimental and Clinical Infection Research, Hannover Medical School and the Helmholtz Center for Infection Research, Hannover 30625, Germany; Institute of Medical Microbiology and Hygiene, University Medical Center of the Johannes Gutenberg-U
Immunity ; 54(1): 68-83.e6, 2021 01 12.
Article em En | MEDLINE | ID: mdl-33238133
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos Cíclicos / Ribossomos / Encefalomielite Autoimune Experimental / Células Th17 / Linezolida / Antibacterianos / Mitocôndrias Limite: Animals / Humans Idioma: En Revista: Immunity Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2021 Tipo de documento: Article
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos Cíclicos / Ribossomos / Encefalomielite Autoimune Experimental / Células Th17 / Linezolida / Antibacterianos / Mitocôndrias Limite: Animals / Humans Idioma: En Revista: Immunity Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2021 Tipo de documento: Article