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Voltage-gated sodium channel Nav1.5 promotes tumor progression and enhances chemosensitivity to 5-fluorouracil in colorectal cancer.
Sui, Qiaoqi; Peng, Jianhong; Han, Kai; Lin, Junzhong; Zhang, Rongxin; Ou, Qingjian; Qin, Jiayi; Deng, Yuxiang; Zhou, Wenhao; Kong, Lingheng; Tang, Jinghua; Xiao, Binyi; Li, Yuan; Yu, Long; Fang, Yujing; Ding, Pei-Rong; Pan, Zhizhong.
Afiliação
  • Sui Q; Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, 510060, PR China; State Key Laboratory of Oncology in South China, Guangzhou, 510060, PR China; Collaborative Innovation Center for Cancer Medicine, Guangzhou, 510060, PR China.
  • Peng J; Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, 510060, PR China; State Key Laboratory of Oncology in South China, Guangzhou, 510060, PR China; Collaborative Innovation Center for Cancer Medicine, Guangzhou, 510060, PR China.
  • Han K; Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, 510060, PR China; State Key Laboratory of Oncology in South China, Guangzhou, 510060, PR China; Collaborative Innovation Center for Cancer Medicine, Guangzhou, 510060, PR China.
  • Lin J; Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, 510060, PR China; State Key Laboratory of Oncology in South China, Guangzhou, 510060, PR China; Collaborative Innovation Center for Cancer Medicine, Guangzhou, 510060, PR China.
  • Zhang R; Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, 510060, PR China; State Key Laboratory of Oncology in South China, Guangzhou, 510060, PR China; Collaborative Innovation Center for Cancer Medicine, Guangzhou, 510060, PR China.
  • Ou Q; Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, 510060, PR China; Department of Experimental Research, Sun Yat-sen University Cancer Center, Guangzhou, 510060, PR China; State Key Laboratory of Oncology in South China, Guangzhou, 510060, PR China; Collaborative Inn
  • Qin J; Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, 510060, PR China; Department of Experimental Research, Sun Yat-sen University Cancer Center, Guangzhou, 510060, PR China; State Key Laboratory of Oncology in South China, Guangzhou, 510060, PR China; Collaborative Inn
  • Deng Y; Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, 510060, PR China; State Key Laboratory of Oncology in South China, Guangzhou, 510060, PR China; Collaborative Innovation Center for Cancer Medicine, Guangzhou, 510060, PR China.
  • Zhou W; Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, 510060, PR China; State Key Laboratory of Oncology in South China, Guangzhou, 510060, PR China; Collaborative Innovation Center for Cancer Medicine, Guangzhou, 510060, PR China.
  • Kong L; Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, 510060, PR China; State Key Laboratory of Oncology in South China, Guangzhou, 510060, PR China; Collaborative Innovation Center for Cancer Medicine, Guangzhou, 510060, PR China.
  • Tang J; Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, 510060, PR China; State Key Laboratory of Oncology in South China, Guangzhou, 510060, PR China; Collaborative Innovation Center for Cancer Medicine, Guangzhou, 510060, PR China.
  • Xiao B; Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, 510060, PR China; State Key Laboratory of Oncology in South China, Guangzhou, 510060, PR China; Collaborative Innovation Center for Cancer Medicine, Guangzhou, 510060, PR China.
  • Li Y; Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, 510060, PR China; State Key Laboratory of Oncology in South China, Guangzhou, 510060, PR China; Collaborative Innovation Center for Cancer Medicine, Guangzhou, 510060, PR China.
  • Yu L; Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, 510060, PR China; State Key Laboratory of Oncology in South China, Guangzhou, 510060, PR China; Collaborative Innovation Center for Cancer Medicine, Guangzhou, 510060, PR China.
  • Fang Y; Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, 510060, PR China; Department of Experimental Research, Sun Yat-sen University Cancer Center, Guangzhou, 510060, PR China; State Key Laboratory of Oncology in South China, Guangzhou, 510060, PR China; Collaborative Inn
  • Ding PR; Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, 510060, PR China; State Key Laboratory of Oncology in South China, Guangzhou, 510060, PR China; Collaborative Innovation Center for Cancer Medicine, Guangzhou, 510060, PR China. Electronic address: dingpr@sysucc.org.c
  • Pan Z; Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, 510060, PR China; State Key Laboratory of Oncology in South China, Guangzhou, 510060, PR China; Collaborative Innovation Center for Cancer Medicine, Guangzhou, 510060, PR China. Electronic address: panzhzh@sysucc.org.
Cancer Lett ; 500: 119-131, 2021 03 01.
Article em En | MEDLINE | ID: mdl-33338532

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Calmodulina / Neoplasias Colorretais / Proteínas Proto-Oncogênicas p21(ras) / Canal de Sódio Disparado por Voltagem NAV1.5 / Fluoruracila Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Cancer Lett Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Calmodulina / Neoplasias Colorretais / Proteínas Proto-Oncogênicas p21(ras) / Canal de Sódio Disparado por Voltagem NAV1.5 / Fluoruracila Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Cancer Lett Ano de publicação: 2021 Tipo de documento: Article