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Pharmacological inactivation of the prion protein by targeting a folding intermediate.
Spagnolli, Giovanni; Massignan, Tania; Astolfi, Andrea; Biggi, Silvia; Rigoli, Marta; Brunelli, Paolo; Libergoli, Michela; Ianeselli, Alan; Orioli, Simone; Boldrini, Alberto; Terruzzi, Luca; Bonaldo, Valerio; Maietta, Giulia; Lorenzo, Nuria L; Fernandez, Leticia C; Codeseira, Yaiza B; Tosatto, Laura; Linsenmeier, Luise; Vignoli, Beatrice; Petris, Gianluca; Gasparotto, Dino; Pennuto, Maria; Guella, Graziano; Canossa, Marco; Altmeppen, Hermann C; Lolli, Graziano; Biressi, Stefano; Pastor, Manuel M; Requena, Jesús R; Mancini, Ines; Barreca, Maria L; Faccioli, Pietro; Biasini, Emiliano.
Afiliação
  • Spagnolli G; Department of Cellular, Computational and Integrative Biology, University of Trento, 38123, Povo, TN, Italy.
  • Massignan T; Dulbecco Telethon Institute, University of Trento, 38123, Povo, TN, Italy.
  • Astolfi A; Department of Cellular, Computational and Integrative Biology, University of Trento, 38123, Povo, TN, Italy.
  • Biggi S; Dulbecco Telethon Institute, University of Trento, 38123, Povo, TN, Italy.
  • Rigoli M; Sibylla Biotech SRL, 37121, Verona, VR, Italy.
  • Brunelli P; Department of Pharmaceutical Sciences, University of Perugia, 06123, Perugia, PG, Italy.
  • Libergoli M; Department of Cellular, Computational and Integrative Biology, University of Trento, 38123, Povo, TN, Italy.
  • Ianeselli A; Dulbecco Telethon Institute, University of Trento, 38123, Povo, TN, Italy.
  • Orioli S; Department of Physics, University of Trento, Povo, Trento, TN, Italy.
  • Boldrini A; Department of Cellular, Computational and Integrative Biology, University of Trento, 38123, Povo, TN, Italy.
  • Terruzzi L; Dulbecco Telethon Institute, University of Trento, 38123, Povo, TN, Italy.
  • Bonaldo V; Department of Cellular, Computational and Integrative Biology, University of Trento, 38123, Povo, TN, Italy.
  • Maietta G; Dulbecco Telethon Institute, University of Trento, 38123, Povo, TN, Italy.
  • Lorenzo NL; Department of Cellular, Computational and Integrative Biology, University of Trento, 38123, Povo, TN, Italy.
  • Fernandez LC; Dulbecco Telethon Institute, University of Trento, 38123, Povo, TN, Italy.
  • Codeseira YB; Department of Physics, University of Trento, Povo, Trento, TN, Italy.
  • Tosatto L; INFN-TIFPA, University of Trento, Povo, Trento, TN, Italy.
  • Linsenmeier L; Department of Cellular, Computational and Integrative Biology, University of Trento, 38123, Povo, TN, Italy.
  • Vignoli B; Sibylla Biotech SRL, 37121, Verona, VR, Italy.
  • Petris G; Department of Cellular, Computational and Integrative Biology, University of Trento, 38123, Povo, TN, Italy.
  • Gasparotto D; Sibylla Biotech SRL, 37121, Verona, VR, Italy.
  • Pennuto M; Department of Cellular, Computational and Integrative Biology, University of Trento, 38123, Povo, TN, Italy.
  • Guella G; Dulbecco Telethon Institute, University of Trento, 38123, Povo, TN, Italy.
  • Canossa M; Department of Cellular, Computational and Integrative Biology, University of Trento, 38123, Povo, TN, Italy.
  • Altmeppen HC; Dulbecco Telethon Institute, University of Trento, 38123, Povo, TN, Italy.
  • Lolli G; CIMUS Biomedical Research Institute, University of Santiago de Compostela-IDIS, Santiago de Compostela, Spain.
  • Biressi S; CIMUS Biomedical Research Institute, University of Santiago de Compostela-IDIS, Santiago de Compostela, Spain.
  • Pastor MM; CIMUS Biomedical Research Institute, University of Santiago de Compostela-IDIS, Santiago de Compostela, Spain.
  • Requena JR; Institute of Biophysics, National Council of Research, 38123 Povo, Trento, TN, Italy.
  • Mancini I; Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, 20246, Hamburg, Germany.
  • Barreca ML; Department of Physics, University of Trento, Povo, Trento, TN, Italy.
  • Faccioli P; Department of Cellular, Computational and Integrative Biology, University of Trento, 38123, Povo, TN, Italy.
  • Biasini E; Department of Cellular, Computational and Integrative Biology, University of Trento, 38123, Povo, TN, Italy.
Commun Biol ; 4(1): 62, 2021 01 12.
Article em En | MEDLINE | ID: mdl-33437023
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dobramento de Proteína / Doenças Priônicas / Avaliação Pré-Clínica de Medicamentos / Proteínas Priônicas Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Commun Biol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Itália
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dobramento de Proteína / Doenças Priônicas / Avaliação Pré-Clínica de Medicamentos / Proteínas Priônicas Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Commun Biol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Itália