Electron Transfer from Haem to the Di-Iron Ferroxidase Centre in Bacterioferritin.
Angew Chem Int Ed Engl
; 60(15): 8376-8379, 2021 04 06.
Article
em En
| MEDLINE
| ID: mdl-33460502
ABSTRACT
The iron redox cycle in ferritins is not completely understood. Bacterioferritins are distinct from other ferritins in that they contain haem groups. It is acknowledged that the two iron motifs in bacterioferritins, the di-nuclear ferroxidase centre and the haem B group, play key roles in two opposing processes, iron sequestration and iron mobilisation, respectively, and the two redox processes are independent. Herein, we show that in Escherichia coli bacterioferritin, there is an electron transfer pathway from the haem to the ferroxidase centre suggesting a new role(s) haem might play in bacterioferritins.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Proteínas de Bactérias
/
Ceruloplasmina
/
Grupo dos Citocromos b
/
Ferritinas
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Heme
Idioma:
En
Revista:
Angew Chem Int Ed Engl
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Reino Unido