Predatory bacteria as living antibiotics - where are we now?
Microbiology (Reading)
; 167(1)2021 01.
Article
em En
| MEDLINE
| ID: mdl-33465024
ABSTRACT
Antimicrobial resistance (AMR) is a global health and economic crisis. With too few antibiotics in development to meet current and anticipated needs, there is a critical need for new therapies to treat Gram-negative infections. One potential approach is the use of living predatory bacteria, such as Bdellovibrio bacteriovorus (small Gram-negative bacteria that naturally invade and kill Gram-negative pathogens of humans, animals and plants). Moving toward the use of Bdellovibrio as a 'living antibiotic' demands the investigation and characterization of these bacterial predators in biologically relevant systems. We review the fundamental science supporting the feasibility of predatory bacteria as alternatives to antibiotics.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Bdellovibrio bacteriovorus
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Bactérias Gram-Positivas
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Antibiose
Limite:
Animals
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Humans
Idioma:
En
Revista:
Microbiology (Reading)
Assunto da revista:
MICROBIOLOGIA
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Reino Unido