Week 96 subgroup analyses of the phase 3, randomized AMBER and EMERALD trials evaluating the efficacy and safety of the once daily darunavir/cobicistat/emtricitabine/tenofovir alafenamide (D/C/F/TAF) single-tablet regimen in antiretroviral treatment (ART)-naïve and -experienced, virologically-suppressed adults living with HIV-1.

Huhn, Gregory D; Wilkin, Aimee; Mussini, Cristina; Spinner, Christoph D; Jezorwski, John; El Ghazi, Mohsine; Van Landuyt, Erika; Lathouwers, Erkki; Brown, Kimberley; Baugh, Bryan

Huhn, Gregory D; Wilkin, Aimee; Mussini, Cristina; Spinner, Christoph D; Jezorwski, John; El Ghazi, Mohsine; Van Landuyt, Erika; Lathouwers, Erkki; Brown, Kimberley; Baugh, Bryan.

Afiliação

Huhn GD; Ruth M. Rothstein CORE Center, Chicago, IL, USA.
Wilkin A; Section on Infectious Diseases, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Mussini C; Department of Infectious Diseases, University of Modena and Reggio Emilia, Modena, Italy.
Spinner CD; School of Medicine, Technical University of Munich, Munich, Germany.
Jezorwski J; Janssen Research and Development LLC, Pennington, NJ, USA.
El Ghazi M; Janssen Pharmaceutica NV, Beerse, Belgium.
Van Landuyt E; Janssen Pharmaceutica NV, Beerse, Belgium.
Lathouwers E; Janssen Pharmaceutica NV, Beerse, Belgium.
Brown K; Janssen Pharmaceutica NV, Beerse, Belgium.
Baugh B; Janssen Research and Development LLC, Raritan, NJ, USA.

HIV Res Clin Pract ; 21(6): 151-167, 2020 12.

Article em En | MEDLINE | ID: mdl-33528318

Assuntos

Fármacos Anti-HIV; Infecções por HIV; HIV-1; Adulto; Alanina; Fármacos Anti-HIV/efeitos adversos; Cobicistat; Darunavir/efeitos adversos; Emtricitabina; Infecções por HIV/tratamento farmacológico; HIV-1/genética; Humanos; Pessoa de Meia-Idade; Comprimidos/farmacologia; Comprimidos/uso terapêutico; Tenofovir/análogos & derivados

Palavras-chave

D/C/F/TAF; HIV-1; Phase III; darunavir; single-tablet regimen; subgroup analysis; tenofovir alafenamide

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções por HIV / HIV-1 / Fármacos Anti-HIV Tipo de estudo: Clinical_trials Limite: Adult / Humans / Middle aged Idioma: En Revista: HIV Res Clin Pract Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos

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