A triple-targeting inhibitory activity of Rose Bengal on polysaccharide biosynthesis of Burkholderia pseudomallei.

Kim, Suwon; Jo, Seri; Kim, Mi-Sun; Shin, Dong H

Kim, Suwon; Jo, Seri; Kim, Mi-Sun; Shin, Dong H.

Afiliação

Kim S; Department of Pharmacy, College of Pharmacy and Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, Republic of Korea.
Jo S; Department of Pharmacy, College of Pharmacy and Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, Republic of Korea.
Kim MS; Department of Pharmacy, College of Pharmacy and Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, Republic of Korea.
Shin DH; Department of Pharmacy, College of Pharmacy and Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, Republic of Korea.

Arch Pharm (Weinheim) ; 354(6): e2000360, 2021 Jun.

Article em En | MEDLINE | ID: mdl-33555065

Assuntos

Burkholderia pseudomallei; Melioidose; Nucleotidiltransferases/antagonistas & inibidores; Polissacarídeos Bacterianos/biossíntese; Rosa Bengala/farmacologia; Antibacterianos/farmacologia; Burkholderia pseudomallei/efeitos dos fármacos; Burkholderia pseudomallei/enzimologia; Desenho de Fármacos; Inibidores Enzimáticos/farmacologia; Humanos; Concentração Inibidora 50; Melioidose/tratamento farmacológico; Melioidose/microbiologia

Palavras-chave

3-deoxy-d-manno-oct-2-ulosonic acid cytidylyltransferase (KdsB); Rose Bengal; d-glycero-α- d-manno-heptose-1-phosphate guanylyltransferase (HddC); d-glycero-ß- d-manno-heptose-1-phosphate adenylyltransferase (HldC); sugar nucleotidyltransferases

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Polissacarídeos Bacterianos / Rosa Bengala / Burkholderia pseudomallei / Melioidose / Nucleotidiltransferases Limite: Humans Idioma: En Revista: Arch Pharm (Weinheim) Ano de publicação: 2021 Tipo de documento: Article

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