Intraepithelial autoimmune bullous dermatoses disease activity assessment and therapy.

Montagnon, Carmen M; Lehman, Julia S; Murrell, Dedee F; Camilleri, Michael J; Tolkachjov, Stanislav N

Montagnon, Carmen M; Lehman, Julia S; Murrell, Dedee F; Camilleri, Michael J; Tolkachjov, Stanislav N.

Afiliação

Montagnon CM; Department of Dermatology, Mayo Clinic, Rochester, Minnesota.
Lehman JS; Department of Dermatology, Mayo Clinic, Rochester, Minnesota; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota.
Murrell DF; Department of Dermatology, St George Hospital, University of New South Wales, Sydney, Australia.
Camilleri MJ; Department of Dermatology, Mayo Clinic, Rochester, Minnesota; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota.
Tolkachjov SN; Epiphany Dermatology, Dallas, Texas. Electronic address: Stan.tolkachjov@gmail.com.

J Am Acad Dermatol ; 84(6): 1523-1537, 2021 Jun.

Article em En | MEDLINE | ID: mdl-33684497

ABSTRACT

ABSTRACT

Intraepithelial autoimmune blistering dermatoses are a rare group of skin disorders characterized by disruptions of inter-keratinocyte connections within the epidermis through the action of autoantibodies. The second article in this continuing medical education series presents validated disease activity scoring systems, serologic parameters of disease, treatments, and clinical trials for pemphigus and its subtypes.

Assuntos

Autoanticorpos/sangue; Doenças Autoimunes/terapia; Fatores Imunológicos/uso terapêutico; Troca Plasmática; Dermatopatias Vesiculobolhosas/terapia; Administração Cutânea; Administração Oral; Autoanticorpos/imunologia; Doenças Autoimunes/sangue; Doenças Autoimunes/diagnóstico; Doenças Autoimunes/imunologia; Quimioterapia Combinada/métodos; Humanos; Injeções Intralesionais; Índice de Gravidade de Doença; Pele/imunologia; Pele/patologia; Dermatopatias Vesiculobolhosas/sangue; Dermatopatias Vesiculobolhosas/diagnóstico; Dermatopatias Vesiculobolhosas/imunologia; Resultado do Tratamento

Palavras-chave

IVIG; Pemphigus Disease Activity Index; azathioprine; dapsone; intraepithelial autoimmune bullous dermatoses; mycophenolate mofetil; paraneoplastic pemphigus/paraneoplastic autoimmune multiorgan syndrome; pemphigus erythematosus; pemphigus foliaceus; pemphigus herpetiformis; pemphigus vulgaris; rituximab

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Troca Plasmática / Autoanticorpos / Doenças Autoimunes / Dermatopatias Vesiculobolhosas / Fatores Imunológicos Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Revista: J Am Acad Dermatol Ano de publicação: 2021 Tipo de documento: Article

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