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Safety, Tolerability, and Pharmacokinetics of a Long-Acting Broadly Neutralizing Human Immunodeficiency Virus Type 1 (HIV-1) Monoclonal Antibody VRC01LS in HIV-1-Exposed Newborn Infants.
McFarland, Elizabeth J; Cunningham, Coleen K; Muresan, Petronella; Capparelli, Edmund V; Perlowski, Charlotte; Morgan, Patricia; Smith, Betsy; Hazra, Rohan; Purdue, Lynette; Harding, Paul A; Theron, Gerhard; Mujuru, Hilda; Agwu, Allison; Purswani, Murli; Rathore, Mobeen H; Flach, Britta; Taylor, Alison; Lin, Bob C; McDermott, Adrian B; Mascola, John R; Graham, Barney S.
Afiliação
  • McFarland EJ; Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
  • Cunningham CK; Department of Pediatrics, Duke University School of Medicine, Durham, North Carolina, USA.
  • Muresan P; Statistical and Data Management Center/Frontier Science Foundation, Brookline, Massachusetts, USA.
  • Capparelli EV; Departments of Pediatrics and Pharmacy, School of Medicine and Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA, USA.
  • Perlowski C; FHI 360, Durham, North Carolina, USA.
  • Morgan P; FHI 360, Durham, North Carolina, USA.
  • Smith B; Division of AIDS, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA.
  • Hazra R; Maternal and Pediatric Infectious Disease Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland, USA.
  • Purdue L; Division of AIDS, National Institute of Allergy and Infectious Diseases, National Institutes of Health (Contractor), Bethesda, Maryland, USA.
  • Harding PA; Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
  • Theron G; Department of Pediatrics and Department of Obstetrics and Gynaecology, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
  • Mujuru H; University of Zimbabwe College of Health Sciences-Clinical Trials Research Centre, Harare, Zimbabwe.
  • Agwu A; Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Purswani M; Department of Pediatrics, BronxCare Health Systems, affiliated with Icahn School of Medicine at Mount Sinai, Bronx, New York, USA.
  • Rathore MH; University of Florida Center for HIV/AIDS Research, Education and Service, University of Florida College of Medicine, Jacksonville, Florida, USA.
  • Flach B; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
  • Taylor A; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
  • Lin BC; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
  • McDermott AB; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
  • Mascola JR; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
  • Graham BS; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
J Infect Dis ; 224(11): 1916-1924, 2021 12 01.
Article em En | MEDLINE | ID: mdl-34009371

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Anticorpos Anti-HIV / Infecções por HIV / HIV-1 / Transmissão Vertical de Doenças Infecciosas / Antirretrovirais / Anticorpos Amplamente Neutralizantes / Anticorpos Monoclonais Limite: Female / Humans / Male / Newborn Idioma: En Revista: J Infect Dis Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Anticorpos Anti-HIV / Infecções por HIV / HIV-1 / Transmissão Vertical de Doenças Infecciosas / Antirretrovirais / Anticorpos Amplamente Neutralizantes / Anticorpos Monoclonais Limite: Female / Humans / Male / Newborn Idioma: En Revista: J Infect Dis Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos