An Autopsy Case of Multicentric Castleman Disease Presenting with Severe Jaundice.
Intern Med
; 60(22): 3615-3620, 2021 Nov 15.
Article
em En
| MEDLINE
| ID: mdl-34092729
ABSTRACT
A 70-year-old man with multicentric Castleman disease (MCD) was admitted to our hospital with jaundice and ascites. Elevations in his bilirubin and interleukin-6 levels were noted, and computed tomography revealed hepatic atrophy and portal vein and bile duct disorders. Steroid therapy was started for MCD, but he died of hepatic failure. An autopsy revealed that the MCD activity was mild, but advanced fibrosis and cholestasis were observed in the liver. Mild infiltration of interleukin-6-positive plasma cells was noted in the highly fibrotic area of the liver. Although rare, liver and biliary tract damage may be also considered organ disorders of MCD.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Hiperplasia do Linfonodo Gigante
/
Falência Hepática
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Icterícia
Tipo de estudo:
Diagnostic_studies
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Etiology_studies
Limite:
Aged
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Humans
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Male
Idioma:
En
Revista:
Intern Med
Assunto da revista:
MEDICINA INTERNA
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Japão