Inositol-Requiring Enzyme 1&#945;-Mediated Synthesis of Monounsaturated Fatty Acids as a Driver of B Cell Differentiation and Lupus-like Autoimmune Disease.

Zhang, Yana; Gui, Ming; Wang, Yajun; Mani, Nikita; Chaudhuri, Shuvam; Gao, Beixue; Li, Huabin; Kanwar, Yashpal S; Lewis, Sarah A; Dumas, Sabrina N; Ntambi, James M; Zhang, Kezhong; Fang, Deyu

Inositol-Requiring Enzyme 1α-Mediated Synthesis of Monounsaturated Fatty Acids as a Driver of B Cell Differentiation and Lupus-like Autoimmune Disease.

Zhang, Yana; Gui, Ming; Wang, Yajun; Mani, Nikita; Chaudhuri, Shuvam; Gao, Beixue; Li, Huabin; Kanwar, Yashpal S; Lewis, Sarah A; Dumas, Sabrina N; Ntambi, James M; Zhang, Kezhong; Fang, Deyu.

Afiliação

Zhang Y; The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, and Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Gui M; Third Xiangya Hospital of Central South University, Changsha, China.
Wang Y; Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Mani N; Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Chaudhuri S; Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Gao B; Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Li H; Affiliated Eye, Ear, Nose, and Throat Hospital, Fudan University, Shanghai, China.
Kanwar YS; Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Lewis SA; University of Wisconsin-Madison.
Dumas SN; University of Wisconsin-Madison.
Ntambi JM; University of Wisconsin-Madison.
Zhang K; Wayne State University School of Medicine, Detroit, Michigan.
Fang D; Northwestern University Feinberg School of Medicine, Chicago, Illinois.

Arthritis Rheumatol ; 73(12): 2314-2326, 2021 12.

Article em En | MEDLINE | ID: mdl-34105254

Assuntos

Doenças Autoimunes/genética; Linfócitos B/metabolismo; Diferenciação Celular/genética; Endorribonucleases/genética; Ácidos Graxos Monoinsaturados/metabolismo; Lúpus Eritematoso Sistêmico/genética; Proteínas Serina-Treonina Quinases/genética; Estearoil-CoA Dessaturase/genética; Animais; Doenças Autoimunes/metabolismo; Endorribonucleases/metabolismo; Humanos; Metabolismo dos Lipídeos/genética; Lúpus Eritematoso Sistêmico/metabolismo; Camundongos; Camundongos Knockout; Proteínas Serina-Treonina Quinases/metabolismo; Estearoil-CoA Dessaturase/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doenças Autoimunes / Estearoil-CoA Dessaturase / Ácidos Graxos Monoinsaturados / Linfócitos B / Diferenciação Celular / Proteínas Serina-Treonina Quinases / Endorribonucleases / Lúpus Eritematoso Sistêmico Limite: Animals / Humans Idioma: En Revista: Arthritis Rheumatol Ano de publicação: 2021 Tipo de documento: Article

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