Inclusion Complexes of Gold(I)-Dithiocarbamates with ß-Cyclodextrin: A Journey from Drug Repurposing towards Drug Discovery.

Morgen, Michael; Fabrowski, Piotr; Amtmann, Eberhard; Gunkel, Nikolas; Miller, Aubry K

Morgen, Michael; Fabrowski, Piotr; Amtmann, Eberhard; Gunkel, Nikolas; Miller, Aubry K.

Afiliação

Morgen M; Cancer Drug Development Group (A390), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.
Fabrowski P; Cancer Drug Development Group (A390), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.
Amtmann E; Cancer Drug Development Group (A390), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.
Gunkel N; Cancer Drug Development Group (A390), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.
Miller AK; German Cancer Consortium (DKTK), 69120, Heidelberg, Germany.

Chemistry ; 27(47): 12156-12165, 2021 Aug 19.

Article em En | MEDLINE | ID: mdl-34114261

Assuntos

Reposicionamento de Medicamentos; beta-Ciclodextrinas; Descoberta de Drogas; Ouro; Humanos; Solubilidade; Difração de Raios X

Palavras-chave

beta-cyclodextrin; drug repurposing; gold dithiocarbamates; host-guest interactions; inclusion complexes

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Beta-Ciclodextrinas / Reposicionamento de Medicamentos Limite: Humans Idioma: En Revista: Chemistry Assunto da revista: QUIMICA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Alemanha

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