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Human GPR17 missense variants identified in metabolic disease patients have distinct downstream signaling profiles.
Conley, Jason M; Sun, Hongmao; Ayers, Kristin L; Zhu, Hu; Chen, Rong; Shen, Min; Hall, Matthew D; Ren, Hongxia.
Afiliação
  • Conley JM; Herman B. Wells Center for Pediatric Research, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana, USA; Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, Indiana, USA.
  • Sun H; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, USA.
  • Ayers KL; Department of Genetics and Genomic Sciences, The Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York, USA; Sema4, a Mount Sinai venture, Stamford, Connecticut, USA.
  • Zhu H; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, USA.
  • Chen R; Department of Genetics and Genomic Sciences, The Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York, USA; Sema4, a Mount Sinai venture, Stamford, Connecticut, USA.
  • Shen M; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, USA.
  • Hall MD; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, USA.
  • Ren H; Herman B. Wells Center for Pediatric Research, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana, USA; Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, Indiana, USA; Department of Pharmacology & Toxicology, Indi
J Biol Chem ; 297(1): 100881, 2021 07.
Article em En | MEDLINE | ID: mdl-34144038
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Mutação de Sentido Incorreto / Síndrome Metabólica / Receptores Acoplados a Proteínas G Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Mutação de Sentido Incorreto / Síndrome Metabólica / Receptores Acoplados a Proteínas G Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos