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Low-dose Aspirin prevents hypertension and cardiac fibrosis when thromboxane A2 is unrestrained.
D'Agostino, Ilaria; Tacconelli, Stefania; Bruno, Annalisa; Contursi, Annalisa; Mucci, Luciana; Hu, Xiaoyue; Xie, Yi; Chakraborty, Raja; Jain, Kanika; Sacco, Angela; Zucchelli, Mirco; Landolfi, Raffaele; Dovizio, Melania; Falcone, Lorenza; Ballerini, Patrizia; Hwa, John; Patrignani, Paola.
Afiliação
  • D'Agostino I; Department of Neuroscience, Imaging and Clinical Sciences, "G. d'Annunzio" University, School of Medicine, Chieti, Italy; CAST (Center for Advanced Studies and Technology), "G. d'Annunzio" University, School of Medicine, Chieti, Italy.
  • Tacconelli S; Department of Neuroscience, Imaging and Clinical Sciences, "G. d'Annunzio" University, School of Medicine, Chieti, Italy; CAST (Center for Advanced Studies and Technology), "G. d'Annunzio" University, School of Medicine, Chieti, Italy.
  • Bruno A; Department of Neuroscience, Imaging and Clinical Sciences, "G. d'Annunzio" University, School of Medicine, Chieti, Italy; CAST (Center for Advanced Studies and Technology), "G. d'Annunzio" University, School of Medicine, Chieti, Italy.
  • Contursi A; Department of Neuroscience, Imaging and Clinical Sciences, "G. d'Annunzio" University, School of Medicine, Chieti, Italy; CAST (Center for Advanced Studies and Technology), "G. d'Annunzio" University, School of Medicine, Chieti, Italy.
  • Mucci L; CAST (Center for Advanced Studies and Technology), "G. d'Annunzio" University, School of Medicine, Chieti, Italy; Department of Medical Science, Catholic University, Rome, Italy.
  • Hu X; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.
  • Xie Y; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.
  • Chakraborty R; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.
  • Jain K; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.
  • Sacco A; Department of Neuroscience, Imaging and Clinical Sciences, "G. d'Annunzio" University, School of Medicine, Chieti, Italy; CAST (Center for Advanced Studies and Technology), "G. d'Annunzio" University, School of Medicine, Chieti, Italy.
  • Zucchelli M; CAST (Center for Advanced Studies and Technology), "G. d'Annunzio" University, School of Medicine, Chieti, Italy.
  • Landolfi R; Department of Medical Science, Catholic University, Rome, Italy.
  • Dovizio M; Department of Neuroscience, Imaging and Clinical Sciences, "G. d'Annunzio" University, School of Medicine, Chieti, Italy; CAST (Center for Advanced Studies and Technology), "G. d'Annunzio" University, School of Medicine, Chieti, Italy.
  • Falcone L; CAST (Center for Advanced Studies and Technology), "G. d'Annunzio" University, School of Medicine, Chieti, Italy; Department of Innovative Technologies in Medicine and Dentistry, "G. d'Annunzio" University, School of Medicine, Chieti, Italy.
  • Ballerini P; CAST (Center for Advanced Studies and Technology), "G. d'Annunzio" University, School of Medicine, Chieti, Italy; Department of Innovative Technologies in Medicine and Dentistry, "G. d'Annunzio" University, School of Medicine, Chieti, Italy.
  • Hwa J; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA. Electronic address: john.hwa@yale.edu.
  • Patrignani P; Department of Neuroscience, Imaging and Clinical Sciences, "G. d'Annunzio" University, School of Medicine, Chieti, Italy; CAST (Center for Advanced Studies and Technology), "G. d'Annunzio" University, School of Medicine, Chieti, Italy. Electronic address: ppatrignani@unich.it.
Pharmacol Res ; 170: 105744, 2021 08.
Article em En | MEDLINE | ID: mdl-34182131
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tromboxano A2 / Plaquetas / Pressão Sanguínea / Inibidores da Agregação Plaquetária / Aspirina / Miócitos Cardíacos / Hipertensão Essencial / Antifibróticos / Cardiomiopatias / Anti-Hipertensivos Tipo de estudo: Etiology_studies / Observational_studies / Risk_factors_studies Limite: Adult / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Pharmacol Res Assunto da revista: FARMACOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Itália
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tromboxano A2 / Plaquetas / Pressão Sanguínea / Inibidores da Agregação Plaquetária / Aspirina / Miócitos Cardíacos / Hipertensão Essencial / Antifibróticos / Cardiomiopatias / Anti-Hipertensivos Tipo de estudo: Etiology_studies / Observational_studies / Risk_factors_studies Limite: Adult / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Pharmacol Res Assunto da revista: FARMACOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Itália