Development and Full Validation of a Bioanalytical Method for Quantifying Letermovir in Human Plasma Using Ultra-Performance Liquid Chromatography Coupled with Mass Spectrometry.

Belabbas, Tassadit; Yamada, Takaaki; Tsuchiya, Yuichi; Suetsugu, Kimitaka; Egashira, Nobuaki; Ieiri, Ichiro

Belabbas, Tassadit; Yamada, Takaaki; Tsuchiya, Yuichi; Suetsugu, Kimitaka; Egashira, Nobuaki; Ieiri, Ichiro.

Afiliação

Belabbas T; Department of Clinical Pharmacology and Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Kyushu University.
Yamada T; Department of Pharmacy, Kyushu University Hospital.
Tsuchiya Y; Department of Pharmacy, Kyushu University Hospital.
Suetsugu K; Department of Pharmacy, Kyushu University Hospital.
Egashira N; Department of Clinical Pharmacology and Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Kyushu University.
Ieiri I; Department of Pharmacy, Kyushu University Hospital.

Chem Pharm Bull (Tokyo) ; 69(7): 646-651, 2021.

Article em En | MEDLINE | ID: mdl-34193713

Assuntos

Acetatos/sangue; Cromatografia Líquida de Alta Pressão/métodos; Quinazolinas/sangue; Espectrometria de Massas em Tandem/métodos; Acetatos/farmacocinética; Antivirais/sangue; Antivirais/farmacocinética; Meia-Vida; Humanos; Limite de Detecção; Quinazolinas/farmacocinética; Reprodutibilidade dos Testes

Palavras-chave

bioanalytical method development; human plasma; letermovir; ultra-performance liquid chromatography coupled with mass spectrometry; validation

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Quinazolinas / Cromatografia Líquida de Alta Pressão / Espectrometria de Massas em Tandem / Acetatos Limite: Humans Idioma: En Revista: Chem Pharm Bull (Tokyo) Ano de publicação: 2021 Tipo de documento: Article

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