Proteomic Profiling of Ectosomes Derived from Paired Urothelial Bladder Cancer and Normal Cells Reveals the Presence of Biologically-Relevant Molecules.

Surman, Magdalena; Kedracka-Krok, Sylwia; Jankowska, Urszula; Drozdz, Anna; Stepien, Ewa; Przybylo, Malgorzata

Surman, Magdalena; Kedracka-Krok, Sylwia; Jankowska, Urszula; Drozdz, Anna; Stepien, Ewa; Przybylo, Malgorzata.

Afiliação

Surman M; Department of Glycoconjugate Biochemistry, Institute of Zoology and Biomedical Research, Faculty of Biology, Jagiellonian University in Kraków, 30-387 Kraków, Poland.
Kedracka-Krok S; Department of Physical Biochemistry, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University in Kraków, 30-387 Kraków, Poland.
Jankowska U; Proteomics and Mass Spectrometry Core Facility, Malopolska Centre of Biotechnology, Jagiellonian University in Kraków, 30-387 Kraków, Poland.
Drozdz A; Department of Medical Physics, M. Smoluchowski Institute of Physics, Faculty of Physics, Astronomy and Applied Computer Science, Jagiellonian University in Kraków, 30-348 Kraków, Poland.
Stepien E; Department of Medical Physics, M. Smoluchowski Institute of Physics, Faculty of Physics, Astronomy and Applied Computer Science, Jagiellonian University in Kraków, 30-348 Kraków, Poland.
Przybylo M; Department of Glycoconjugate Biochemistry, Institute of Zoology and Biomedical Research, Faculty of Biology, Jagiellonian University in Kraków, 30-387 Kraków, Poland.

Int J Mol Sci ; 22(13)2021 Jun 24.

Article em En | MEDLINE | ID: mdl-34202855

Assuntos

Exossomos/metabolismo; Proteoma; Proteômica; Neoplasias da Bexiga Urinária/metabolismo; Biomarcadores Tumorais; Carcinoma de Células de Transição/metabolismo; Estudos de Casos e Controles; Linhagem Celular Tumoral; Micropartículas Derivadas de Células/metabolismo; Cromatografia Líquida; Biologia Computacional/métodos; Progressão da Doença; Vesículas Extracelulares/metabolismo; Humanos; Proteômica/métodos; Espectrometria de Massas em Tandem

Palavras-chave

biomarkers; bladder cancer; ectosomes; extracellular vesicles; mass spectrometry; nanoLC-MS/MS; proteomics

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Bexiga Urinária / Proteoma / Proteômica / Exossomos Tipo de estudo: Observational_studies / Qualitative_research Limite: Humans Idioma: En Revista: Int J Mol Sci Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Polônia

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