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Serine-linked PARP1 auto-modification controls PARP inhibitor response.
Prokhorova, Evgeniia; Zobel, Florian; Smith, Rebecca; Zentout, Siham; Gibbs-Seymour, Ian; Schützenhofer, Kira; Peters, Alessandra; Groslambert, Joséphine; Zorzini, Valentina; Agnew, Thomas; Brognard, John; Nielsen, Michael L; Ahel, Dragana; Huet, Sébastien; Suskiewicz, Marcin J; Ahel, Ivan.
Afiliação
  • Prokhorova E; Sir William Dunn School of Pathology, University of Oxford, Oxford, UK.
  • Zobel F; Sir William Dunn School of Pathology, University of Oxford, Oxford, UK.
  • Smith R; Univ Rennes, CNRS, Structure Fédérative de Recherche Biosit, IGDR (Institut de Génétique et Développement de Rennes) - UMR 6290, Rennes, France.
  • Zentout S; Univ Rennes, CNRS, Structure Fédérative de Recherche Biosit, IGDR (Institut de Génétique et Développement de Rennes) - UMR 6290, Rennes, France.
  • Gibbs-Seymour I; Sir William Dunn School of Pathology, University of Oxford, Oxford, UK.
  • Schützenhofer K; Department of Biochemistry, University of Oxford, Oxford, UK.
  • Peters A; Sir William Dunn School of Pathology, University of Oxford, Oxford, UK.
  • Groslambert J; Sir William Dunn School of Pathology, University of Oxford, Oxford, UK.
  • Zorzini V; Sir William Dunn School of Pathology, University of Oxford, Oxford, UK.
  • Agnew T; Sir William Dunn School of Pathology, University of Oxford, Oxford, UK.
  • Brognard J; Sir William Dunn School of Pathology, University of Oxford, Oxford, UK.
  • Nielsen ML; Laboratory of Cell and Developmental Signaling, Center for Cancer Research, National Cancer Institute, Frederick, MD, USA.
  • Ahel D; Proteomics Program, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Huet S; Sir William Dunn School of Pathology, University of Oxford, Oxford, UK.
  • Suskiewicz MJ; Univ Rennes, CNRS, Structure Fédérative de Recherche Biosit, IGDR (Institut de Génétique et Développement de Rennes) - UMR 6290, Rennes, France.
  • Ahel I; Institut Universitaire de France, Paris, France.
Nat Commun ; 12(1): 4055, 2021 07 01.
Article em En | MEDLINE | ID: mdl-34210965

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Serina / Dano ao DNA / Proteínas Nucleares / Proteínas de Transporte / Reparo do DNA / Inibidores de Poli(ADP-Ribose) Polimerases / Poli(ADP-Ribose) Polimerase-1 / Neoplasias Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Serina / Dano ao DNA / Proteínas Nucleares / Proteínas de Transporte / Reparo do DNA / Inibidores de Poli(ADP-Ribose) Polimerases / Poli(ADP-Ribose) Polimerase-1 / Neoplasias Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido