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Nicotinamide phosphoribosyltransferase inhibitors selectively induce apoptosis of AML stem cells by disrupting lipid homeostasis.
Subedi, Amit; Liu, Qiang; Ayyathan, Dhanoop M; Sharon, David; Cathelin, Severine; Hosseini, Mohsen; Xu, Changjiang; Voisin, Veronique; Bader, Gary D; D'Alessandro, Angelo; Lechman, Eric R; Dick, John E; Minden, Mark D; Wang, Jean C Y; Chan, Steven M.
Afiliação
  • Subedi A; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Liu Q; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Ayyathan DM; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Sharon D; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Cathelin S; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Hosseini M; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Xu C; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada; Donnelly Centre for Cellular and Biomolecular Research, Toronto, ON, Canada.
  • Voisin V; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada; Donnelly Centre for Cellular and Biomolecular Research, Toronto, ON, Canada.
  • Bader GD; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada; Donnelly Centre for Cellular and Biomolecular Research, Toronto, ON, Canada.
  • D'Alessandro A; Department of Biochemistry and Molecular Genetics, University of Colorado Denver, Aurora, CO, USA.
  • Lechman ER; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Dick JE; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.
  • Minden MD; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada; Department of Medicine, University of Toronto, ON, Canada; Division of Medical Oncology and Hematology, Department of Medicine, University Health Network, Toronto, ON, Canada.
  • Wang JCY; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada; Department of Medicine, University of Toronto, ON, Canada; Division of Medical Oncology and Hematology, Department of Medicine, University Health Network, Toronto, ON, Canada.
  • Chan SM; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada; Department of Medicine, University of Toronto, ON, Canada; Division of Medical Oncology and Hematology, Department of Medicine, University Health Network, Toronto, ON, Canada. Electronic address: steven.chan@uhnresearch
Cell Stem Cell ; 28(10): 1851-1867.e8, 2021 10 07.
Article em En | MEDLINE | ID: mdl-34293334
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Nicotinamida Fosforribosiltransferase Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Cell Stem Cell Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Canadá
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Nicotinamida Fosforribosiltransferase Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Cell Stem Cell Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Canadá