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Solution structures of human myeloma IgG3 antibody reveal extended Fab and Fc regions relative to the other IgG subclasses.
Spiteri, Valentina A; Goodall, Margaret; Doutch, James; Rambo, Robert P; Gor, Jayesh; Perkins, Stephen J.
Afiliação
  • Spiteri VA; Department of Structural and Molecular Biology, Division of Biosciences, University College London, London, United Kingdom.
  • Goodall M; Institute for Biomedical Research, University of Birmingham, Birmingham, United Kingdom.
  • Doutch J; ISIS Facility, STFC Rutherford Appleton Laboratory, Harwell Campus, Didcot, Oxfordshire, United Kingdom.
  • Rambo RP; Diamond Light Source Ltd, Harwell Science and Innovation Campus, Didcot, Oxfordshire, United Kingdom.
  • Gor J; Department of Structural and Molecular Biology, Division of Biosciences, University College London, London, United Kingdom.
  • Perkins SJ; Department of Structural and Molecular Biology, Division of Biosciences, University College London, London, United Kingdom. Electronic address: s.perkins@ucl.ac.uk.
J Biol Chem ; 297(3): 100995, 2021 09.
Article em En | MEDLINE | ID: mdl-34302810
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Imunoglobulina G / Fragmentos Fab das Imunoglobulinas / Proteínas do Mieloma / Receptores Fc / Mieloma Múltiplo Limite: Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Imunoglobulina G / Fragmentos Fab das Imunoglobulinas / Proteínas do Mieloma / Receptores Fc / Mieloma Múltiplo Limite: Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido