Fused in sarcoma regulates DNA replication timing and kinetics.

Jia, Weiyan; Kim, Sang Hwa; Scalf, Mark A; Tonzi, Peter; Millikin, Robert J; Guns, William M; Liu, Lu; Mastrocola, Adam S; Smith, Lloyd M; Huang, Tony T; Tibbetts, Randal S

Jia, Weiyan; Kim, Sang Hwa; Scalf, Mark A; Tonzi, Peter; Millikin, Robert J; Guns, William M; Liu, Lu; Mastrocola, Adam S; Smith, Lloyd M; Huang, Tony T; Tibbetts, Randal S.

Afiliação

Jia W; Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Kim SH; Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Scalf MA; Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Tonzi P; Department of Biochemistry and Molecular Pharmacology, New York University Langone Health, New York, New York, USA.
Millikin RJ; Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Guns WM; Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Liu L; Department of Biostatistics and Medical Informatics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Mastrocola AS; Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Smith LM; Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Huang TT; Department of Biochemistry and Molecular Pharmacology, New York University Langone Health, New York, New York, USA.
Tibbetts RS; Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA. Electronic address: rstibbetts@wisc.edu.

J Biol Chem ; 297(3): 101049, 2021 09.

Article em En | MEDLINE | ID: mdl-34375640

Assuntos

Período de Replicação do DNA; Proteína FUS de Ligação a RNA/metabolismo; Sarcoma/genética; Sarcoma/metabolismo; Proteína BRCA1/genética; Proteína BRCA1/metabolismo; Proliferação de Células; Quebras de DNA de Cadeia Dupla; Reparo do DNA; Humanos; Cinética; Proteína FUS de Ligação a RNA/genética; Proteína 1 de Ligação à Proteína Supressora de Tumor p53/genética; Proteína 1 de Ligação à Proteína Supressora de Tumor p53/metabolismo

Palavras-chave

DNA repair; DNA replication; RNA binding protein; amyotrophic lateral sclerosis (ALS); fused in sarcoma (FUS); replication timing

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sarcoma / Proteína FUS de Ligação a RNA / Período de Replicação do DNA Limite: Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos

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