<i>Lrig1</i> expression identifies airway basal cells with high proliferative capacity and restricts lung squamous cell carcinoma growth.

Succony, Laura; Gómez-López, Sandra; Pennycuick, Adam; Alhendi, Ahmed S N; Davies, Derek; Clarke, Sarah E; Gowers, Kate H C; Wright, Nicholas A; Jensen, Kim B; Janes, Sam M

Lrig1 expression identifies airway basal cells with high proliferative capacity and restricts lung squamous cell carcinoma growth.

Succony, Laura; Gómez-López, Sandra; Pennycuick, Adam; Alhendi, Ahmed S N; Davies, Derek; Clarke, Sarah E; Gowers, Kate H C; Wright, Nicholas A; Jensen, Kim B; Janes, Sam M.

Afiliação

Succony L; Lungs for Living Research Centre, UCL Respiratory, University College London, London, UK.
Gómez-López S; These authors contributed equally to this work.
Pennycuick A; Lungs for Living Research Centre, UCL Respiratory, University College London, London, UK.
Alhendi ASN; These authors contributed equally to this work.
Davies D; Lungs for Living Research Centre, UCL Respiratory, University College London, London, UK.
Clarke SE; Lungs for Living Research Centre, UCL Respiratory, University College London, London, UK.
Gowers KHC; Flow Cytometry Facility, Francis Crick Institute, London, UK.
Wright NA; Lungs for Living Research Centre, UCL Respiratory, University College London, London, UK.
Jensen KB; Lungs for Living Research Centre, UCL Respiratory, University College London, London, UK.
Janes SM; Centre for Tumour Biology, Barts Cancer Institute, Queen Mary University of London, London, UK.

Eur Respir J ; 59(3)2022 03.

Article em En | MEDLINE | ID: mdl-34385275

Assuntos

Carcinoma Pulmonar de Células não Pequenas; Carcinoma de Células Escamosas; Neoplasias Pulmonares; Animais; Carcinoma de Células Escamosas/genética; Carcinoma de Células Escamosas/patologia; Humanos; Pulmão/patologia; Neoplasias Pulmonares/genética; Neoplasias Pulmonares/patologia; Glicoproteínas de Membrana/efeitos adversos; Glicoproteínas de Membrana/genética; Glicoproteínas de Membrana/metabolismo; Camundongos; Proteínas do Tecido Nervoso/metabolismo; Oncogenes

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma de Células Escamosas / Carcinoma Pulmonar de Células não Pequenas / Neoplasias Pulmonares Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Eur Respir J Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Reino Unido

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