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The Polycomb protein RING1B enables estrogen-mediated gene expression by promoting enhancer-promoter interaction and R-loop formation.
Zhang, Yusheng; Liu, Tong; Yuan, Fenghua; Garcia-Martinez, Liliana; Lee, Kyutae D; Stransky, Stephanie; Sidoli, Simone; Verdun, Ramiro E; Zhang, Yanbin; Wang, Zheng; Morey, Lluis.
Afiliação
  • Zhang Y; Sylvester Comprehensive Cancer Center, Biomedical Research Building, 1501 NW 10th Avenue, Miami, FL 33136, USA.
  • Liu T; Department of Human Genetics, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
  • Yuan F; Department of Computer Science, University of Miami, 1365 Memorial Drive, P.O. Box 248154, Coral Gables, FL 33124, USA.
  • Garcia-Martinez L; Sylvester Comprehensive Cancer Center, Biomedical Research Building, 1501 NW 10th Avenue, Miami, FL 33136, USA.
  • Lee KD; Department of Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
  • Stransky S; Sylvester Comprehensive Cancer Center, Biomedical Research Building, 1501 NW 10th Avenue, Miami, FL 33136, USA.
  • Sidoli S; Department of Human Genetics, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
  • Verdun RE; Sylvester Comprehensive Cancer Center, Biomedical Research Building, 1501 NW 10th Avenue, Miami, FL 33136, USA.
  • Zhang Y; Department of Human Genetics, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
  • Wang Z; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
  • Morey L; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Nucleic Acids Res ; 49(17): 9768-9782, 2021 09 27.
Article em En | MEDLINE | ID: mdl-34428304
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ativação Transcricional / Elementos Facilitadores Genéticos / Regiões Promotoras Genéticas / Estradiol / Complexo Repressor Polycomb 1 / Estruturas R-Loop Limite: Humans Idioma: En Revista: Nucleic Acids Res Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ativação Transcricional / Elementos Facilitadores Genéticos / Regiões Promotoras Genéticas / Estradiol / Complexo Repressor Polycomb 1 / Estruturas R-Loop Limite: Humans Idioma: En Revista: Nucleic Acids Res Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos