Dual film-like organelles enable spatial separation of orthogonal eukaryotic translation.

Reinkemeier, Christopher D; Lemke, Edward A

Reinkemeier, Christopher D; Lemke, Edward A.

Afiliação

Reinkemeier CD; Biocentre, Departments of Biology and Chemistry, Johannes Gutenberg University Mainz, Hanns-Dieter-Hüsch-Weg 17, 55128 Mainz, Germany; Institute of Molecular Biology gGmbH, Ackermannweg 4, 55128 Mainz, Germany; Structural and Computational Biology Unit and Cell Biology and Biophysics Unit, European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany.
Lemke EA; Biocentre, Departments of Biology and Chemistry, Johannes Gutenberg University Mainz, Hanns-Dieter-Hüsch-Weg 17, 55128 Mainz, Germany; Institute of Molecular Biology gGmbH, Ackermannweg 4, 55128 Mainz, Germany; Structural and Computational Biology Unit and Cell Biology and Biophysics Unit, European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany. Electronic address: edlemke@uni-mainz.de.

Cell ; 184(19): 4886-4903.e21, 2021 09 16.

Article em En | MEDLINE | ID: mdl-34433013

Assuntos

Células Eucarióticas/metabolismo; Organelas/metabolismo; Biossíntese de Proteínas; Aminoácidos/metabolismo; Código Genético; Células HEK293; Humanos; Membranas Intracelulares/metabolismo; RNA Mensageiro/genética; RNA Mensageiro/metabolismo; Ribossomos/metabolismo

Palavras-chave

2D phase separation; enzyme engineering; genetic code expansion; membrane signaling; orthogonal translation; synthetic biology; synthetic biomolecular condensates

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Biossíntese de Proteínas / Organelas / Células Eucarióticas Limite: Humans Idioma: En Revista: Cell Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Alemanha

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