Frizzled<sub>7</sub> Activates ß-Catenin-Dependent and ß-Catenin-Independent Wnt Signalling Pathways During Developmental Morphogenesis: Implications for Therapeutic Targeting in Colorectal Cancer.

Tran, Bang Manh; Flanagan, Dustin James; Phesse, Toby James; Vincan, Elizabeth

Frizzled₇ Activates ß-Catenin-Dependent and ß-Catenin-Independent Wnt Signalling Pathways During Developmental Morphogenesis: Implications for Therapeutic Targeting in Colorectal Cancer.

Tran, Bang Manh; Flanagan, Dustin James; Phesse, Toby James; Vincan, Elizabeth.

Afiliação

Tran BM; Department of Infectious Diseases, Melbourne Medical School, University of Melbourne, Melbourne, VIC, Australia.
Flanagan DJ; The Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia.
Phesse TJ; The Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia.
Vincan E; Cancer Research UK Beatson Institute, Glasgow, UK.

Handb Exp Pharmacol ; 269: 251-277, 2021.

Article em En | MEDLINE | ID: mdl-34455486

Assuntos

Neoplasias Colorretais; Receptores Frizzled; Morfogênese; Via de Sinalização Wnt; beta Catenina; Animais; Neoplasias Colorretais/tratamento farmacológico; Humanos; beta Catenina/metabolismo

Palavras-chave

Cancer; Drug discovery; FZD; FZD7; Frizzled; Frizzled7; PCP; Wnt; Wnt/Ca++ pathway; ß-catenin

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Beta Catenina / Receptores Frizzled / Via de Sinalização Wnt / Morfogênese Limite: Animals / Humans Idioma: En Revista: Handb Exp Pharmacol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Austrália

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