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Cortical overgrowth in a preclinical forebrain organoid model of CNTNAP2-associated autism spectrum disorder.
de Jong, Job O; Llapashtica, Ceyda; Genestine, Matthieu; Strauss, Kevin; Provenzano, Frank; Sun, Yan; Zhu, Huixiang; Cortese, Giuseppe P; Brundu, Francesco; Brigatti, Karlla W; Corneo, Barbara; Migliori, Bianca; Tomer, Raju; Kushner, Steven A; Kellendonk, Christoph; Javitch, Jonathan A; Xu, Bin; Markx, Sander.
Afiliação
  • de Jong JO; Department of Psychiatry, Vagelos College of Physicians & Surgeons, Columbia University, New York, NY, USA.
  • Llapashtica C; Division of Molecular Therapeutics, New York State Psychiatric Institute, New York, NY, USA.
  • Genestine M; Department of Psychiatry, Vagelos College of Physicians & Surgeons, Columbia University, New York, NY, USA.
  • Strauss K; Division of Molecular Therapeutics, New York State Psychiatric Institute, New York, NY, USA.
  • Provenzano F; Department of Psychiatry, Vagelos College of Physicians & Surgeons, Columbia University, New York, NY, USA.
  • Sun Y; Division of Molecular Therapeutics, New York State Psychiatric Institute, New York, NY, USA.
  • Zhu H; Clinic for Special Children, Strasburg, PA, USA.
  • Cortese GP; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University, New York, NY, USA.
  • Brundu F; Department of Psychiatry, Vagelos College of Physicians & Surgeons, Columbia University, New York, NY, USA.
  • Brigatti KW; Department of Psychiatry, Vagelos College of Physicians & Surgeons, Columbia University, New York, NY, USA.
  • Corneo B; Division of Molecular Therapeutics, New York State Psychiatric Institute, New York, NY, USA.
  • Migliori B; Department of Psychiatry, Vagelos College of Physicians & Surgeons, Columbia University, New York, NY, USA.
  • Tomer R; Division of Molecular Therapeutics, New York State Psychiatric Institute, New York, NY, USA.
  • Kushner SA; Department of Systems Biology, Columbia University, New York, NY, USA.
  • Kellendonk C; Clinic for Special Children, Strasburg, PA, USA.
  • Javitch JA; Stem Cell Core Facility, Columbia University, New York, NY, USA.
  • Xu B; Tech4Health and Neuroscience Institutes, NYU Langone Health, New York, NY, USA.
  • Markx S; Department of Biological Sciences, Columbia University, New York, NY, USA.
Nat Commun ; 12(1): 4087, 2021 09 01.
Article em En | MEDLINE | ID: mdl-34471112

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Organoides / Prosencéfalo / Transtorno do Espectro Autista / Proteínas de Membrana / Proteínas do Tecido Nervoso Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Adolescent / Child / Female / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Organoides / Prosencéfalo / Transtorno do Espectro Autista / Proteínas de Membrana / Proteínas do Tecido Nervoso Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Adolescent / Child / Female / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos