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Heparin remodels the microtubule-binding repeat R3 of Tau protein towards fibril-prone conformations.
Dong, Xuewei; Qi, Ruxi; Qiao, Qin; Li, Xuhua; Li, Fangying; Wan, Jiaqian; Zhang, Qingwen; Wei, Guanghong.
Afiliação
  • Dong X; Department of Physics, State Key Laboratory of Surface Physics, and Key Laboratory for Computational Physical Sciences (Ministry of Education), Fudan University, Shanghai 200438, People's Republic of China. ghwei@fudan.edu.cn.
  • Qi R; Cryo-EM Center, Southern University of Science and Technology, Shenzhen, 518055, People's Republic of China.
  • Qiao Q; Digital Medical Research Center, School of Basic Medical Sciences, Shanghai Key Laboratory of Medical Imaging Computing and Computer Assisted Intervention, Fudan University, Shanghai 200032, People's Republic of China.
  • Li X; MOE Key Laboratory for Nonequilibrium Synthesis and Modulation of Condensed Matter, School of Physics, Xi'an Jiaotong University, Xi'an 710049, People's Republic of China.
  • Li F; Department of Physics, State Key Laboratory of Surface Physics, and Key Laboratory for Computational Physical Sciences (Ministry of Education), Fudan University, Shanghai 200438, People's Republic of China. ghwei@fudan.edu.cn.
  • Wan J; College of Physical Education and Training, Shanghai University of Sport, Shanghai 200438, People's Republic of China.
  • Zhang Q; College of Physical Education and Training, Shanghai University of Sport, Shanghai 200438, People's Republic of China.
  • Wei G; Department of Physics, State Key Laboratory of Surface Physics, and Key Laboratory for Computational Physical Sciences (Ministry of Education), Fudan University, Shanghai 200438, People's Republic of China. ghwei@fudan.edu.cn.
Phys Chem Chem Phys ; 23(36): 20406-20418, 2021 Sep 22.
Article em En | MEDLINE | ID: mdl-34494046
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Heparina / Proteínas tau / Simulação de Dinâmica Molecular / Amiloide Limite: Humans Idioma: En Revista: Phys Chem Chem Phys Assunto da revista: BIOFISICA / QUIMICA Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Heparina / Proteínas tau / Simulação de Dinâmica Molecular / Amiloide Limite: Humans Idioma: En Revista: Phys Chem Chem Phys Assunto da revista: BIOFISICA / QUIMICA Ano de publicação: 2021 Tipo de documento: Article