Immunoregulatory T cell epitope peptides for the treatment of allergic disease.
Immunotherapy
; 13(15): 1283-1291, 2021 10.
Article
em En
| MEDLINE
| ID: mdl-34558985
Lay abstract Allergen immunotherapy is the only disease-modifying treatment option for patients with chronic allergic rhinitis, typically featuring formulations to promote the development of immune tolerance. Although effective, the use of whole allergen has been found to promote unintended IgE crosslinking, resulting in local and systemic adverse effects. To overcome such limitations, the use of T-cell epitope peptides in allergen immunotherapy has been explored with hopeful outcomes. Compared with allergen immunotherapy, peptide immunotherapy is quicker, safer and more efficacious, making it quite promising. Although peptides for pet dander, honeybee venom, pollen and house dust mite allergies have been developed, more extensive research is necessary to prior to widespread usage.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Hipersensibilidade Respiratória
/
Dessensibilização Imunológica
/
Epitopos de Linfócito T
Tipo de estudo:
Risk_factors_studies
Limite:
Humans
Idioma:
En
Revista:
Immunotherapy
Assunto da revista:
ALERGIA E IMUNOLOGIA
/
TERAPEUTICA
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Canadá