Image-based deep learning reveals the responses of human motor neurons to stress and VCP-related ALS.

Verzat, Colombine; Harley, Jasmine; Patani, Rickie; Luisier, Raphaëlle

Verzat, Colombine; Harley, Jasmine; Patani, Rickie; Luisier, Raphaëlle.

Afiliação

Verzat C; Genomics and Health Informatics Group, Idiap Research Institute, Martigny, Switzerland.
Harley J; Human Stem Cells and Neurodegeneration Laboratory, The Francis Crick Institute, London, UK.
Patani R; Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, London, UK.
Luisier R; Human Stem Cells and Neurodegeneration Laboratory, The Francis Crick Institute, London, UK.

Neuropathol Appl Neurobiol ; 48(2): e12770, 2022 02.

Article em En | MEDLINE | ID: mdl-34595747

Assuntos

Esclerose Lateral Amiotrófica/metabolismo; Aprendizado Profundo; Neurônios Motores/metabolismo; Neuritos/metabolismo; Humanos; Células-Tronco Pluripotentes Induzidas/metabolismo; Fenótipo

Palavras-chave

amyotrophic lateral sclerosis; deep learning; human induced pluripotent stem cells; immunofluorescence; motor neurons

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neuritos / Aprendizado Profundo / Esclerose Lateral Amiotrófica / Neurônios Motores Limite: Humans Idioma: En Revista: Neuropathol Appl Neurobiol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Suíça

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