Left parietal involvement in motion sickness susceptibility revealed by multimodal magnetic resonance imaging.
Hum Brain Mapp
; 43(3): 1103-1111, 2022 02 15.
Article
em En
| MEDLINE
| ID: mdl-34783415
ABSTRACT
Susceptibility to motion sickness varies greatly across individuals. However, the neural mechanisms underlying this susceptibility remain largely unclear. To address this gap, the current study aimed to identify the neural correlates of motion sickness susceptibility using multimodal MRI. First, we compared resting-state functional connectivity between healthy individuals who were highly susceptible to motion sickness (N = 36) and age/sex-matched controls who showed low susceptibility (N = 36). Seed-based analysis revealed between-group differences in functional connectivity of core vestibular regions in the left posterior Sylvian fissure. A data-driven approach using intrinsic connectivity contrast found greater network centrality of the left intraparietal sulcus in high- rather than in low-susceptible individuals. Moreover, exploratory structural connectivity analysis uncovered an association between motion sickness susceptibility and white matter integrity in the left inferior fronto-occipital fasciculus. Taken together, our data indicate left parietal involvement in motion sickness susceptibility.
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Córtex Cerebral
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Enjoo devido ao Movimento
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Imagem Ecoplanar
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Imagem de Difusão por Ressonância Magnética
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Conectoma
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Substância Branca
Limite:
Adult
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Hum Brain Mapp
Assunto da revista:
CEREBRO
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Japão