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Structure-function analysis for macular surgery in patients with coexisting glaucoma.
Yu, Sarah N; Hood, Donald C; Blumberg, Dana M; Chang, Stanley; Greenstein, Vivienne C.
Afiliação
  • Yu SN; Department of Ophthalmology, Columbia University, New York, NY, USA.
  • Hood DC; Department of Ophthalmology, Columbia University, New York, NY, USA.
  • Blumberg DM; Department of Psychology, Columbia University, 160 Fort Washington Avenue, Room 508, New York, NY, 10032, USA.
  • Chang S; Department of Ophthalmology, Columbia University, New York, NY, USA.
  • Greenstein VC; Department of Ophthalmology, Columbia University, New York, NY, USA.
Graefes Arch Clin Exp Ophthalmol ; 260(5): 1475-1489, 2022 May.
Article em En | MEDLINE | ID: mdl-34783892
PURPOSE: To develop methods to assess the effects of epiretinal membranes (ERM) and macular holes (MH) coexisting with glaucoma on pre-operative retinal structure and function and evaluate post-operative outcomes. METHODS: Seven eyes of 7 patients with glaucoma, 6 with ERMs and 1 with MH, were enrolled; 4 underwent vitrectomy for ERM and one for MH. Visual fields (VFs) and optical coherence tomography (OCT) scans were obtained pre- and post-operatively. The 10-2VF deviation map was overlayed on ganglion cell and inner plexiform layer (GCL + IPL) and retinal nerve fiber layer (RNFL) deviation maps derived from OCT macula and disc cube scans. Optic nerve circle scans were obtained to assess RNFL thickness, and OCT b-scans associated with VF defects were compared pre- and post-operatively. RESULTS: Examination of pre-operative VFs and OCT scans showed the importance of determining the extent to which glaucomatous damage contributed to VF loss; verifying automated segmentation of the GCL + IPL and RNFL; and assessing foveal anatomy. Evaluation of post-operative structure-function outcomes required correction of magnification changes in OCT scans and repeated follow-up visits to clarify the origin of VF changes. CONCLUSIONS: Pre-operative comparisons of VFs and OCT scans may be beneficial in guiding surgical planning, and evaluating outcomes, in eyes with glaucoma undergoing macular surgery.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Glaucoma / Fibras Nervosas Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Revista: Graefes Arch Clin Exp Ophthalmol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Glaucoma / Fibras Nervosas Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Revista: Graefes Arch Clin Exp Ophthalmol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos