Propofol alleviates postoperative cognitive dysfunction by inhibiting inflammation via up-regulating miR-223-3p in aged rats.

Lian, Fang; Cao, Cao; Deng, Fumou; Liu, Chunfang; Zhou, Zhidong

Lian, Fang; Cao, Cao; Deng, Fumou; Liu, Chunfang; Zhou, Zhidong.

Afiliação

Lian F; Department of Anesthesiology, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, PR China.
Cao C; Department of Anesthesiology, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, PR China.
Deng F; Department of Anesthesiology, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, PR China.
Liu C; Department of Anesthesiology, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, PR China.
Zhou Z; Department of Anesthesiology, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, PR China. Electronic address: zhuzhidong197608@163.com.

Cytokine ; 150: 155783, 2022 02.

Article em En | MEDLINE | ID: mdl-34979347

Assuntos

Disfunção Cognitiva; Isoflurano; MicroRNAs; Complicações Cognitivas Pós-Operatórias; Propofol; Animais; Disfunção Cognitiva/tratamento farmacológico; Humanos; Inflamação/metabolismo; Isoflurano/farmacologia; MicroRNAs/genética; MicroRNAs/metabolismo; Propofol/farmacologia; Ratos

Palavras-chave

Foxo1; Inflammatory response; Memory; Postoperative cognitive dysfunction; Propofol; miR-223-3p

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Propofol / MicroRNAs / Disfunção Cognitiva / Complicações Cognitivas Pós-Operatórias / Isoflurano Limite: Animals / Humans Idioma: En Revista: Cytokine Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2022 Tipo de documento: Article

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