Proteolytic Profiling of Streptococcal Pyrogenic Exotoxin B (SpeB) by Complementary HPLC-MS Approaches.

Blöchl, Constantin; Holzner, Christoph; Luciano, Michela; Bauer, Renate; Horejs-Hoeck, Jutta; Eckhard, Ulrich; Brandstetter, Hans; Huber, Christian G

Blöchl, Constantin; Holzner, Christoph; Luciano, Michela; Bauer, Renate; Horejs-Hoeck, Jutta; Eckhard, Ulrich; Brandstetter, Hans; Huber, Christian G.

Afiliação

Blöchl C; Bioanalytical Research Labs, Department of Biosciences, University of Salzburg, Hellbrunner Strasse 34, 5020 Salzburg, Austria.
Holzner C; Structural Biology, Department of Biosciences, University of Salzburg, Hellbrunner Strasse 34, 5020 Salzburg, Austria.
Luciano M; Molecular Immunology & Signal Transduction, Department of Biosciences, University of Salzburg, Hellbrunner Strasse 34, 5020 Salzburg, Austria.
Bauer R; Cancer Cluster Salzburg, Department of Biosciences, University of Salzburg, Hellbrunner Strasse 34, 5020 Salzburg, Austria.
Horejs-Hoeck J; Molecular Immunology & Signal Transduction, Department of Biosciences, University of Salzburg, Hellbrunner Strasse 34, 5020 Salzburg, Austria.
Eckhard U; Molecular Immunology & Signal Transduction, Department of Biosciences, University of Salzburg, Hellbrunner Strasse 34, 5020 Salzburg, Austria.
Brandstetter H; Cancer Cluster Salzburg, Department of Biosciences, University of Salzburg, Hellbrunner Strasse 34, 5020 Salzburg, Austria.
Huber CG; Structural Biology, Department of Biosciences, University of Salzburg, Hellbrunner Strasse 34, 5020 Salzburg, Austria.

Int J Mol Sci ; 23(1)2021 Dec 30.

Article em En | MEDLINE | ID: mdl-35008838

Assuntos

Proteínas de Bactérias/metabolismo; Exotoxinas/metabolismo; Espectrometria de Massas; Proteólise; Streptococcus pyogenes/metabolismo; Sequência de Aminoácidos; Cromatografia Líquida de Alta Pressão; Escherichia coli/metabolismo; Humanos; Imunoglobulina G/química; Imunoglobulina G/metabolismo; Peptídeo Hidrolases/metabolismo; Peptídeos/metabolismo; Proteoma/metabolismo; Proteínas Recombinantes/metabolismo; Especificidade por Substrato

Palavras-chave

HUNTER; IgG subclasses; N-terminomics; SCP; positional proteomics; protease degradomics; sequence logo; sequence specificity; streptococcal cysteine protease; streptopain

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Espectrometria de Massas / Streptococcus pyogenes / Proteínas de Bactérias / Exotoxinas / Proteólise Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Int J Mol Sci Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Áustria

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