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Development of a ligand for in vivo imaging of mutant huntingtin in Huntington's disease.
Bertoglio, Daniele; Bard, Jonathan; Hessmann, Manuela; Liu, Longbin; Gärtner, Annette; De Lombaerde, Stef; Huscher, Britta; Zajicek, Franziska; Miranda, Alan; Peters, Finn; Herrmann, Frank; Schaertl, Sabine; Vasilkovska, Tamara; Brown, Christopher J; Johnson, Peter D; Prime, Michael E; Mills, Matthew R; Van der Linden, Annemie; Mrzljak, Ladislav; Khetarpal, Vinod; Wang, Yuchuan; Marchionini, Deanna M; Skinbjerg, Mette; Verhaeghe, Jeroen; Dominguez, Celia; Staelens, Steven; Munoz-Sanjuan, Ignacio.
Afiliação
  • Bertoglio D; Molecular Imaging Center Antwerp (MICA), University of Antwerp, Wilrijk 2610, Belgium.
  • Bard J; CHDI Management/CHDI Foundation, Los Angeles, CA 90045, USA.
  • Hessmann M; Evotec SE, Hamburg 22419, Germany.
  • Liu L; CHDI Management/CHDI Foundation, Los Angeles, CA 90045, USA.
  • Gärtner A; Evotec SE, Hamburg 22419, Germany.
  • De Lombaerde S; Molecular Imaging Center Antwerp (MICA), University of Antwerp, Wilrijk 2610, Belgium.
  • Huscher B; Department of Nuclear Medicine, Antwerp University Hospital, Edegem 2650, Belgium.
  • Zajicek F; Evotec SE, Hamburg 22419, Germany.
  • Miranda A; Molecular Imaging Center Antwerp (MICA), University of Antwerp, Wilrijk 2610, Belgium.
  • Peters F; Molecular Imaging Center Antwerp (MICA), University of Antwerp, Wilrijk 2610, Belgium.
  • Herrmann F; Evotec SE, Hamburg 22419, Germany.
  • Schaertl S; Evotec SE, Hamburg 22419, Germany.
  • Vasilkovska T; Evotec SE, Hamburg 22419, Germany.
  • Brown CJ; Bio-Imaging Lab, University of Antwerp, Wilrijk 2610, Belgium.
  • Johnson PD; Evotec Ltd., Abingdon OX14 4RZ, UK.
  • Prime ME; Evotec Ltd., Abingdon OX14 4RZ, UK.
  • Mills MR; Evotec Ltd., Abingdon OX14 4RZ, UK.
  • Van der Linden A; Evotec Ltd., Abingdon OX14 4RZ, UK.
  • Mrzljak L; Bio-Imaging Lab, University of Antwerp, Wilrijk 2610, Belgium.
  • Khetarpal V; CHDI Management/CHDI Foundation, Los Angeles, CA 90045, USA.
  • Wang Y; CHDI Management/CHDI Foundation, Los Angeles, CA 90045, USA.
  • Marchionini DM; CHDI Management/CHDI Foundation, Los Angeles, CA 90045, USA.
  • Skinbjerg M; CHDI Management/CHDI Foundation, Los Angeles, CA 90045, USA.
  • Verhaeghe J; CHDI Management/CHDI Foundation, Los Angeles, CA 90045, USA.
  • Dominguez C; Molecular Imaging Center Antwerp (MICA), University of Antwerp, Wilrijk 2610, Belgium.
  • Staelens S; CHDI Management/CHDI Foundation, Los Angeles, CA 90045, USA.
  • Munoz-Sanjuan I; Molecular Imaging Center Antwerp (MICA), University of Antwerp, Wilrijk 2610, Belgium.
Sci Transl Med ; 14(630): eabm3682, 2022 02 02.
Article em En | MEDLINE | ID: mdl-35108063
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Huntington / Doenças Neurodegenerativas Limite: Animals Idioma: En Revista: Sci Transl Med Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Bélgica
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Huntington / Doenças Neurodegenerativas Limite: Animals Idioma: En Revista: Sci Transl Med Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Bélgica