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Real life experience with the wearable cardioverter-defibrillator in an international multicenter Registry.
El-Battrawy, Ibrahim; Kovacs, Boldizsar; Dreher, Tobias C; Klein, Norbert; Rosenkaimer, Stephanie; Röger, Susanne; Kuschyk, Jürgen; Saguner, Ardan Muammer; Kowitz, Jacqueline; Erath, Julia W; Duru, Firat; Akin, Ibrahim.
Afiliação
  • El-Battrawy I; Bergmannsheil University Medical Center, Ruhr University Bochum, Bochum, Germany. Ibrahim.elbattrawy2006@gmail.com.
  • Kovacs B; Department of Cardiology and Angiology, Bergmannsheil University Hospitals, Ruhr University of Bochum, Bochum, Germany. Ibrahim.elbattrawy2006@gmail.com.
  • Dreher TC; Department of Cardiology, University Heart Center, University Hospital Zurich, Zurich, Switzerland.
  • Klein N; University of Mannheim, Mannheim, Germany.
  • Rosenkaimer S; Department of Cardiology, Angiology and Internal Intensive-Care Medicine, Klinikum St. Georg gGmbH Leipzig, Delitzscher Straße 141, 04129, Leipzig, Germany.
  • Röger S; University of Mannheim, Mannheim, Germany.
  • Kuschyk J; University of Mannheim, Mannheim, Germany.
  • Saguner AM; University of Mannheim, Mannheim, Germany.
  • Kowitz J; Department of Cardiology, University Heart Center, University Hospital Zurich, Zurich, Switzerland.
  • Erath JW; University of Mannheim, Mannheim, Germany.
  • Duru F; Department of Cardiology, Frankfurt University Hospital, Goethe University, Frankfurt am Main, Germany.
  • Akin I; Department of Cardiology, University Heart Center, University Hospital Zurich, Zurich, Switzerland.
Sci Rep ; 12(1): 3203, 2022 02 25.
Article em En | MEDLINE | ID: mdl-35217697
ABSTRACT
Patients at high risk for sudden cardiac death (SCD) may benefit from wearable cardioverter defibrillators (WCD) by avoiding immediate implantable cardioverter defibrillator (ICD) implantation. Different factors play an important role including patient selection, compliance and optimal drug treatment. We aimed to present real world data from 4 centers from Germany and Switzerland. Between 04/2012 and 03/2019, 708 patients were included in this registry. Patients were followed up over a mean time of 28 ± 35.5 months. Outcome data including gender differences and different etiologies of cardiomyopathy were analyzed. Out of 708 patients (81.8% males, mean age 61.0 ± 14.6), 44.6% of patients had non-ischemic cardiomyopathy, 39.8% ischemic cardiomyopathy, 7.9% myocarditis, 5.4% prior need for ICD explantation and 2.1% channelopathy. The mean wear time of WCD was 21.2 ± 4.3 h per day. In 46% of patients, left ventricular ejection fraction (LVEF) was > 35% during follow-up. The younger the patient was, the higher the LVEF and the lower the wear hours per day were. The total shock rate during follow-up was 2.7%. Whereas an appropriate WCD shock was documented in 16 patients (2.2%), 3 patients received an inappropriate ICD shock (0.5%). During follow-up, implantation of a cardiac implantable electronic device was carried out in 34.5% of patients. When comparing German patients (n = 516) to Swiss patients (n = 192), Swiss patients presented with longer wear days (70.72 ± 49.47 days versus 58.06 ± 40.45 days; p = 0.001) and a higher ICD implantation rate compared to German patients (48.4% versus 29.3%; p = 0.001), although LVEF at follow-up was similar between both groups. Young age is a negative independent predictor for the compliance in this large registry. The most common indication for WCD was non-ischemic cardiomyopathy followed by ischemic cardiomyopathy. The compliance rate was generally high with a decrease of wear hours per day at younger age. Slight differences were found between Swiss and German patients, which might be related to differences in mentality for ICD implantation.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Isquemia Miocárdica / Desfibriladores Implantáveis / Dispositivos Eletrônicos Vestíveis / Cardiomiopatias Tipo de estudo: Clinical_trials / Etiology_studies / Prognostic_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Sci Rep Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Alemanha

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Isquemia Miocárdica / Desfibriladores Implantáveis / Dispositivos Eletrônicos Vestíveis / Cardiomiopatias Tipo de estudo: Clinical_trials / Etiology_studies / Prognostic_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Sci Rep Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Alemanha