The case for brakes: Why restrain the size of Bax and Bak pores in outer mitochondrial membranes?
Mol Cell
; 82(5): 882-883, 2022 03 03.
Article
em En
| MEDLINE
| ID: mdl-35245452
ABSTRACT
By comparing the structures of Bax and Bak megapores, Cosentino et al. (2022) reveal new insights suggesting the two pro-apoptotic proteins co-assemble into structures that release DNA from mitochondria and thereby trigger inflammation.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Membranas Mitocondriais
/
Proteína Killer-Antagonista Homóloga a bcl-2
Idioma:
En
Revista:
Mol Cell
Assunto da revista:
BIOLOGIA MOLECULAR
Ano de publicação:
2022
Tipo de documento:
Article