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Significant growth inhibition by a bispecific affibody targeting oncoprotein E7 in both HPV16 and 18 positive cervical cancer in vitro and in vivo.
Tan, Xiaochun; Yang, Jiani; Jiang, Jie; Wang, Wenhuan; Ren, Jiahuan; Li, Qijia; Xie, Zixin; Chen, Xinan; Zhang, Lifang; Li, Wenshu.
Afiliação
  • Tan X; Department of Microbiology and Immunology, Wenzhou Medical University, Wenzhou, Zhejiang, China.
  • Yang J; Department of Microbiology and Immunology, Wenzhou Medical University, Wenzhou, Zhejiang, China.
  • Jiang J; Ningbo No.9 Hospital, Ningbo, Zhejiang, China.
  • Wang W; Department of Reproductive Genetics, Wenzhou Key Laboratory of Gynecology and Obstetrics, the Third Affiliated Hospital of Shanghai University (Wenzhou People's Hospital), Wenzhou, Zhejiang, China.
  • Ren J; Department of General Surgery, the First Affliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
  • Li Q; Department of Microbiology and Immunology, Wenzhou Medical University, Wenzhou, Zhejiang, China.
  • Xie Z; Department of Microbiology and Immunology, Wenzhou Medical University, Wenzhou, Zhejiang, China.
  • Chen X; Department of Microbiology and Immunology, Wenzhou Medical University, Wenzhou, Zhejiang, China.
  • Zhang L; Department of Microbiology and Immunology, Wenzhou Medical University, Wenzhou, Zhejiang, China. Electronic address: lifangzhangwz@126.com.
  • Li W; Department of Microbiology and Immunology, Wenzhou Medical University, Wenzhou, Zhejiang, China. Electronic address: lwswz2019@163.com.
Eur J Pharm Sci ; 172: 106156, 2022 May 01.
Article em En | MEDLINE | ID: mdl-35245683
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias do Colo do Útero / Proteínas Oncogênicas Virais Limite: Female / Humans Idioma: En Revista: Eur J Pharm Sci Assunto da revista: FARMACIA / FARMACOLOGIA / QUIMICA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias do Colo do Útero / Proteínas Oncogênicas Virais Limite: Female / Humans Idioma: En Revista: Eur J Pharm Sci Assunto da revista: FARMACIA / FARMACOLOGIA / QUIMICA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China