Assessments of prolonged effects of desflurane and sevoflurane on motor learning deficits in aged App<sup>NL-G-F/NL-G-F</sup> mice.

Niikura, Ryo; Miyazaki, Tomoyuki; Takase, Kenkichi; Sasaguri, Hiroki; Saito, Takashi; Saido, Takaomi C; Goto, Takahisa

Assessments of prolonged effects of desflurane and sevoflurane on motor learning deficits in aged App^{NL-G-F/NL-G-F} mice.

Niikura, Ryo; Miyazaki, Tomoyuki; Takase, Kenkichi; Sasaguri, Hiroki; Saito, Takashi; Saido, Takaomi C; Goto, Takahisa.

Afiliação

Niikura R; Department of Anesthesiology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Miyazaki T; Department of Anesthesiology, Yokohama City University Graduate School of Medicine, Yokohama, Japan. johney@yokohama-cu.ac.jp.
Takase K; Department of Physiology, Yokohama City University Graduate School of Medicine, Yokohama, Japan. johney@yokohama-cu.ac.jp.
Sasaguri H; Laboratory of Psychology, Jichi Medical University School of Medicine, Simotsuke, Tochigi, Japan. kenkichi.takase@jichi.ac.jp.
Saito T; Laboratory for Proteolytic Neuroscience, RIKEN Center for Brain Science, Wako, Saitama, Japan.
Saido TC; Laboratory for Proteolytic Neuroscience, RIKEN Center for Brain Science, Wako, Saitama, Japan.
Goto T; Department of Neurocognitive Science, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi, Japan.

Mol Brain ; 15(1): 32, 2022 04 07.

Article em En | MEDLINE | ID: mdl-35387663

Assuntos

Doença de Alzheimer; Peptídeos beta-Amiloides; Idoso; Doença de Alzheimer/complicações; Doença de Alzheimer/metabolismo; Peptídeos beta-Amiloides/metabolismo; Precursor de Proteína beta-Amiloide/metabolismo; Animais; Desflurano; Modelos Animais de Doenças; Humanos; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Transgênicos; Sevoflurano/farmacologia

Palavras-chave

Alzheimer's disease; AppNL−G−F/NL−G−F; Behavioral phenotype; General anesthesia; Postanesthetic effects; Transgenic mice

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos beta-Amiloides / Doença de Alzheimer Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Aged / Animals / Humans Idioma: En Revista: Mol Brain Assunto da revista: BIOLOGIA MOLECULAR / CEREBRO Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Japão

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