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Engineered Cas9 extracellular vesicles as a novel gene editing tool.
Osteikoetxea, Xabier; Silva, Andreia; Lázaro-Ibáñez, Elisa; Salmond, Nikki; Shatnyeva, Olga; Stein, Josia; Schick, Jan; Wren, Stephen; Lindgren, Julia; Firth, Mike; Madsen, Alexandra; Mayr, Lorenz M; Overman, Ross; Davies, Rick; Dekker, Niek.
Afiliação
  • Osteikoetxea X; Discovery Biology, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Alderley Park, UK.
  • Silva A; HCEMM-SU Extracellular Vesicles Research Group, Budapest, Hungary.
  • Lázaro-Ibáñez E; Department of Genetics, Cell- and Immunobiology, Semmelweis University, Budapest, Hungary.
  • Salmond N; Discovery Biology, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Shatnyeva O; Discovery Biology, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Stein J; Advanced Drug Delivery, Pharmaceutical Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Schick J; Discovery Biology, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Alderley Park, UK.
  • Wren S; Discovery Biology, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Lindgren J; Discovery Biology, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Alderley Park, UK.
  • Firth M; Discovery Biology, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Alderley Park, UK.
  • Madsen A; Global Product Development, Pharmaceutical Technology & Development, AstraZeneca, Macclesfield, UK.
  • Mayr LM; Translational Genomics, Discovery Biology, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Overman R; Quantitative Biology, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.
  • Davies R; Genome Engineering, Discovery Biology, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Dekker N; Discovery Biology, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.
J Extracell Vesicles ; 11(5): e12225, 2022 05.
Article em En | MEDLINE | ID: mdl-35585651
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vesículas Extracelulares / Edição de Genes Limite: Humans Idioma: En Revista: J Extracell Vesicles Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vesículas Extracelulares / Edição de Genes Limite: Humans Idioma: En Revista: J Extracell Vesicles Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Reino Unido