Preparation of Chromeno[b]quinoline Derivatives and Their Application for Lipid Droplets Markers.
J Org Chem
; 87(15): 10385-10389, 2022 08 05.
Article
em En
| MEDLINE
| ID: mdl-35802521
ABSTRACT
Functional dyes with a chromeno[b]quinoline skeleton (3a-d) were synthesized by one-step cyclization between coumarin derivatives and aromatic amines under the promotion of anhydrous aluminum chloride in 41.2-45.8% yields. Their maximum absorption and emission wavelengths locate at 358-396 and 420-603 nm with large Stokes shifts (168-231 nm), and their intramolecular charge transfer has been corroborated by density functional theory calculations. Cell experiments have proved that the probes 3a-c possess the ability to target lipid droplets.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Quinolinas
/
Gotículas Lipídicas
Idioma:
En
Revista:
J Org Chem
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
China