Insights into the development of pentylenetetrazole-induced epileptic seizures from dynamic metabolomic changes.

Zhao, Xue; Cheng, Peixuan; Xu, Ru; Meng, Kaili; Liao, Sha; Jia, Pu; Zheng, Xiaohui; Xiao, Chaoni

Zhao, Xue; Cheng, Peixuan; Xu, Ru; Meng, Kaili; Liao, Sha; Jia, Pu; Zheng, Xiaohui; Xiao, Chaoni.

Afiliação

Zhao X; The College of Life Sciences, Northwest University, 710069, Xi'an, PR China.
Cheng P; The College of Life Sciences, Northwest University, 710069, Xi'an, PR China.
Xu R; The College of Life Sciences, Northwest University, 710069, Xi'an, PR China.
Meng K; The College of Life Sciences, Northwest University, 710069, Xi'an, PR China.
Liao S; The College of Life Sciences, Northwest University, 710069, Xi'an, PR China.
Jia P; The College of Life Sciences, Northwest University, 710069, Xi'an, PR China.
Zheng X; The College of Life Sciences, Northwest University, 710069, Xi'an, PR China.
Xiao C; The College of Life Sciences, Northwest University, 710069, Xi'an, PR China. xiaochaoni@nwu.edu.cn.

Metab Brain Dis ; 37(7): 2441-2455, 2022 10.

Article em En | MEDLINE | ID: mdl-35838870

Assuntos

Epilepsia; Pentilenotetrazol; Animais; Ratos; Alanina; Anticonvulsivantes/uso terapêutico; Asparagina; Citratos; Creatina/uso terapêutico; Creatinina; Modelos Animais de Doenças; Epilepsia/tratamento farmacológico; Glucose; Glutamatos; Isoleucina; Corpos Cetônicos; Lactatos; Leucina; Pentilenotetrazol/toxicidade; Piruvatos; Convulsões/tratamento farmacológico; Succinatos; Valina

Palavras-chave

Nuclear magnetic resonance (NMR)-based metabolomics; Pentylenetetrazole; Seizures

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pentilenotetrazol / Epilepsia Limite: Animals Idioma: En Revista: Metab Brain Dis Assunto da revista: CEREBRO / METABOLISMO Ano de publicação: 2022 Tipo de documento: Article

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