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Anti-GPVI nanobody blocks collagen- and atherosclerotic plaque-induced GPVI clustering, signaling, and thrombus formation.
Jooss, Natalie J; Smith, Christopher W; Slater, Alexandre; Montague, Samantha J; Di, Ying; O'Shea, Christopher; Thomas, Mark R; Henskens, Yvonne M C; Heemskerk, Johan W M; Watson, Steve P; Poulter, Natalie S.
Afiliação
  • Jooss NJ; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
  • Smith CW; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, the Netherlands.
  • Slater A; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
  • Montague SJ; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
  • Di Y; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
  • O'Shea C; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
  • Thomas MR; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
  • Henskens YMC; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
  • Heemskerk JWM; Department of Cardiology, University Hospitals Birmingham, Birmingham, UK.
  • Watson SP; Central Diagnostic Laboratory, Maastricht University Medical Centre, Maastricht, the Netherlands.
  • Poulter NS; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, the Netherlands.
J Thromb Haemost ; 20(11): 2617-2631, 2022 11.
Article em En | MEDLINE | ID: mdl-35894121
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Trombose / Placa Aterosclerótica / Anticorpos de Domínio Único Limite: Humans Idioma: En Revista: J Thromb Haemost Assunto da revista: HEMATOLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Trombose / Placa Aterosclerótica / Anticorpos de Domínio Único Limite: Humans Idioma: En Revista: J Thromb Haemost Assunto da revista: HEMATOLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Reino Unido