&#945;vß3 integrin-specific exosomes engineered with cyclopeptide for targeted delivery of triptolide against malignant melanoma.

Gu, Yongwei; Du, Yue; Jiang, Liangdi; Tang, Xiaomeng; Li, Aixue; Zhao, Yunan; Lang, Yitian; Liu, Xiaoyan; Liu, Jiyong

αvß3 integrin-specific exosomes engineered with cyclopeptide for targeted delivery of triptolide against malignant melanoma.

Gu, Yongwei; Du, Yue; Jiang, Liangdi; Tang, Xiaomeng; Li, Aixue; Zhao, Yunan; Lang, Yitian; Liu, Xiaoyan; Liu, Jiyong.

Afiliação

Gu Y; Department of Pharmacy, Fudan University Shanghai Cancer Center, Fudan University, Shanghai, 200032, China.
Du Y; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, 200032, China.
Jiang L; Department of Pharmacy, Fudan University Shanghai Cancer Center, Fudan University, Shanghai, 200032, China.
Tang X; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, 200032, China.
Li A; Department of Pharmacy, Children's Hospital Affiliated to Shanghai Jiao Tong University, Shanghai, 200062, China.
Zhao Y; Department of Pharmacy, Fudan University Shanghai Cancer Center, Fudan University, Shanghai, 200032, China.
Lang Y; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, 200032, China.
Liu X; School of Pharmacy, Shanghai Jiao Tong University, Shanghai, 200240, China.
Liu J; Department of Pharmacy, Fudan University Shanghai Cancer Center, Fudan University, Shanghai, 200032, China.

J Nanobiotechnology ; 20(1): 384, 2022 Aug 23.

Article em En | MEDLINE | ID: mdl-35999612

Assuntos

Exossomos; Integrina alfaVbeta3/metabolismo; Melanoma; Neoplasias Cutâneas; Animais; Linhagem Celular Tumoral; Diterpenos; Compostos de Epóxi; Exossomos/metabolismo; Humanos; Integrinas/metabolismo; Melanoma/tratamento farmacológico; Melanoma/metabolismo; Camundongos; Peptídeos Cíclicos/metabolismo; Fenantrenos; Neoplasias Cutâneas/tratamento farmacológico; Distribuição Tecidual; Melanoma Maligno Cutâneo

Palavras-chave

Exosomes; Malignant melanoma; Targeted delivery; Triptolide; cRGD

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Integrina alfaVbeta3 / Exossomos / Melanoma Limite: Animals / Humans Idioma: En Revista: J Nanobiotechnology Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China

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