The Amyloid Cascade Hypothesis 2.0: On the Possibility of Once-in-a-Lifetime-Only Treatment for Prevention of Alzheimer's Disease and for Its Potential Cure at Symptomatic Stages.

Volloch, Vladimir; Rits-Volloch, Sophia

Volloch, Vladimir; Rits-Volloch, Sophia.

Afiliação

Volloch V; Department of Developmental Biology, Harvard School of Dental Medicine, Boston, MA, USA.
Rits-Volloch S; Division of Molecular Medicine, Children's Hospital, Boston, MA, USA.

J Alzheimers Dis Rep ; 6(1): 369-399, 2022.

Article em En | MEDLINE | ID: mdl-36072366

Palavras-chave

AßPP-independent generation of iAß; BACE activators as AD drugs; PKR and HRI kinases; iAß depletion therapy for AD; integrated stress response; intraneuronal Aß (iAß); the Amyloid Cascade Hypothesis 2.0

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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies / Prognostic_studies Idioma: En Revista: J Alzheimers Dis Rep Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

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