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Malignant transformation by oncogenic K-ras requires IDH2-mediated reductive carboxylation to promote glutamine utilization.
Liu, Rui; Liu, Panpan; Bi, Huichang; Ling, Jianhua; Zhang, Huiqin; Zhang, Mingquan; Hu, Yumin; Chiao, Paul J; Huang, Peng; Liu, Jinyun.
Afiliação
  • Liu R; Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, Guangdong, 510060, P. R. China.
  • Liu P; School of Materials Science and Engineering, Sun Yat-sen University, Guangzhou, Guangdong, 510275, P. R. China.
  • Bi H; Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, Guangdong, 510060, P. R. China.
  • Ling J; School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, Guangdong, 510515, P. R. China.
  • Zhang H; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, 77030, USA.
  • Zhang M; Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, Guangdong, 510060, P. R. China.
  • Hu Y; Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, Guangdong, 510060, P. R. China.
  • Chiao PJ; Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, Guangdong, 510060, P. R. China.
  • Huang P; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, 77030, USA.
  • Liu J; Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, Guangdong, 510060, P. R. China.
Cancer Commun (Lond) ; 43(2): 285-289, 2023 02.
Article em En | MEDLINE | ID: mdl-36251752

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Glutamina / Isocitrato Desidrogenase Limite: Humans Idioma: En Revista: Cancer Commun (Lond) Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Glutamina / Isocitrato Desidrogenase Limite: Humans Idioma: En Revista: Cancer Commun (Lond) Ano de publicação: 2023 Tipo de documento: Article