Advanced Diffusion MRI for prediction of Stroke Recovery.
J Magn Reson Imaging
; 57(5): 1312-1319, 2023 05.
Article
em En
| MEDLINE
| ID: mdl-36378071
ABSTRACT
There is an urgent need for ways to improve our understanding of poststroke recovery to inform the development of novel rehabilitative interventions, and improve the clinical management of stroke patients. Supported by the notion that predictive information on poststroke recovery is embedded not only in the individual brain regions, but also the connections throughout the brain, majority of previous investigations have focused on the relationship between brain functional connections and post-stroke deficit and recovery. However, considering the fact that it is the static anatomical brain connections that constrain and facilitate the dynamic functional brain connections, the microstructures and structural connections of the brain may potentially be better alternatives to the functional MRI-based biomarkers of stroke recovery. This review, therefore, seeks to provide an overview of the basic concept and applications of two recently proposed advanced diffusion MRI techniques, namely lesion network mapping and fixel-based morphometry, that may be useful for the investigation of stroke recovery at the local and global levels of the brain. This review will also highlight the application of some of other emerging advanced diffusion MRI techniques that warrant further investigation in the context of stroke recovery research.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Acidente Vascular Cerebral
/
Conectoma
Tipo de estudo:
Prognostic_studies
/
Risk_factors_studies
Limite:
Humans
Idioma:
En
Revista:
J Magn Reson Imaging
Assunto da revista:
DIAGNOSTICO POR IMAGEM
Ano de publicação:
2023
Tipo de documento:
Article
País de afiliação:
China