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Cytosolic and mitochondrial tRNA synthetase inhibitors increase lifespan in a GCN4/atf-4-dependent manner.
Robbins, Christine E; Patel, Bhumil; Sawyer, Danielle L; Wilkinson, Barrie; Kennedy, Brian K; McCormick, Mark A.
Afiliação
  • Robbins CE; Department of Biochemistry and Molecular Biology, School of Medicine, University of New Mexico Health Sciences Center, Albuquerque, NM 87131, USA.
  • Patel B; Buck Institute for Research on Aging, Novato, CA 94945, USA.
  • Sawyer DL; Buck Institute for Research on Aging, Novato, CA 94945, USA.
  • Wilkinson B; Department of Molecular Microbiology, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, UK.
  • Kennedy BK; Buck Institute for Research on Aging, Novato, CA 94945, USA.
  • McCormick MA; Departments of Biochemistry and Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119077 Singapore.
iScience ; 25(11): 105410, 2022 Nov 18.
Article em En | MEDLINE | ID: mdl-36388960

Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: IScience Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: IScience Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos