Whole-genome RNA sequencing identifies distinct transcriptomic profiles in impingement cartilage between patients with femoroacetabular impingement and hip osteoarthritis.

Kuhns, Benjamin D; Reuter, John M; Hansen, Victoria L; Soles, Gillian L; Jonason, Jennifer H; Ackert-Bicknell, Cheryl L; Wu, Chia-Lung; Giordano, Brian D

Whole-genome RNA sequencing identifies distinct transcriptomic profiles in impingement cartilage between patients with femoroacetabular impingement and hip osteoarthritis.

Kuhns, Benjamin D; Reuter, John M; Hansen, Victoria L; Soles, Gillian L; Jonason, Jennifer H; Ackert-Bicknell, Cheryl L; Wu, Chia-Lung; Giordano, Brian D.

Afiliação

Kuhns BD; Center for Regenerative and Personalized Medicine, Steadman-Philippon Research Institute, Vail, Colorado, USA.
Reuter JM; Department of Orthopaedics and Rehabilitation, University of Rochester Medical Center, Rochester, New York, USA.
Hansen VL; Department of Orthopaedics and Rehabilitation, University of Rochester Medical Center, Rochester, New York, USA.
Soles GL; Department of Orthopedic Surgery, University of California Davis Health System, Sacramento, California, USA.
Jonason JH; Department of Orthopaedics and Rehabilitation, University of Rochester Medical Center, Rochester, New York, USA.
Ackert-Bicknell CL; Colorado Program for Musculoskeletal Research, Department of Orthopedics, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Wu CL; Department of Orthopaedics and Rehabilitation, University of Rochester Medical Center, Rochester, New York, USA.
Giordano BD; Department of Orthopaedics and Rehabilitation, University of Rochester Medical Center, Rochester, New York, USA.

J Orthop Res ; 41(7): 1517-1530, 2023 07.

Article em En | MEDLINE | ID: mdl-36463522

Assuntos

Cartilagem Articular; Impacto Femoroacetabular; Osteoartrite do Quadril; Humanos; Osteoartrite do Quadril/metabolismo; Impacto Femoroacetabular/complicações; Impacto Femoroacetabular/genética; Articulação do Quadril/patologia; RNA; Transcriptoma; Cartilagem Articular/patologia; Progressão da Doença; Análise de Sequência de RNA

Palavras-chave

bioinformatics; femoroacetabular impingement; hip osteoarthritis; mRNA sequencing

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Osteoartrite do Quadril / Cartilagem Articular / Impacto Femoroacetabular Limite: Humans Idioma: En Revista: J Orthop Res Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

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