Cystatin B deficiency results in sustained histone H3 tail cleavage in postnatal mouse brain mediated by increased chromatin-associated cathepsin L activity.

Daura, Eduard; Tegelberg, Saara; Hakala, Paula; Lehesjoki, Anna-Elina; Joensuu, Tarja

Daura, Eduard; Tegelberg, Saara; Hakala, Paula; Lehesjoki, Anna-Elina; Joensuu, Tarja.

Afiliação

Daura E; Folkhälsan Research Center, Helsinki, Finland.
Tegelberg S; Faculty of Medicine, Medicum, University of Helsinki, Helsinki, Finland.
Hakala P; Folkhälsan Research Center, Helsinki, Finland.
Lehesjoki AE; Faculty of Medicine, Medicum, University of Helsinki, Helsinki, Finland.
Joensuu T; Folkhälsan Research Center, Helsinki, Finland.

Front Mol Neurosci ; 15: 1069122, 2022.

Article em En | MEDLINE | ID: mdl-36533126

Palavras-chave

EPM1; H3cs1; brain development; cathepsin L; cystatin B; histone H3; histone cleavage; senescence

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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Risk_factors_studies Idioma: En Revista: Front Mol Neurosci Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Finlândia

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